Accessible Requires Authentication Published by De Gruyter June 1, 2005

Apoptotic Pathways: Involvement of Lysosomal Proteases

B. Turk, V. Stoka, J. Rozman-Pungercar, T. Cirman, G. Droga-Mazovec, K. Oreic and V. Turk
From the journal

Abstract

Apoptosis or programmed cell death is the major mechanism used by multicellular organisms to remove infected, excessive and potentially dangerous cells. Cysteine proteases from the caspase family play a crucial role in the process. However, there is increasing evidence that lysosomal proteases are also involved in apoptosis. In this review various lysosomal proteases and their potential contribution to propagation of apoptosis are discussed.

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Published Online: 2005-06-01
Published in Print: 2002-08-27

Copyright © 2002 by Walter de Gruyter GmbH & Co. KG