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Licensed Unlicensed Requires Authentication Published by De Gruyter June 1, 2005

Pentanucleotide TTTTA and G/A –914 DNA Polymorphisms in Apolipoprotein(a) Promoter: Genotyping by Single-Tube PCR

Maja Živković, Aleksandra Stanković and Dragan Alavantić
From the journal

Abstract

It is known that pentanucleotide repeat polymorphism, consisting of varying number of (TTTTA) repeats in a promoter, is associated with plasma lipoprotein(a) levels. G/A −914 base substitution has also been correlated with pentanucleotide repeat polymorphism in individuals with high and low lipoprotein(a) levels. To facilitate future analysis of these polymorphisms we have developed a quick and reliable assay for the detection of both polymorphisms in a single polymerase chain reaction.

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Published Online: 2005-06-01
Published in Print: 2003-05-15

Copyright © 2003 by Walter de Gruyter GmbH & Co. KG

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