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Licensed Unlicensed Requires Authentication Published by De Gruyter June 1, 2005

Immunoturbidimetric Determination of C-Reactive Protein (CRP) and High-Sensitivity CRP on Heparin Plasma. Comparison with Serum Determination

  • Anne M. Dupuy , Stéphanie Badiou , Bernard Descomps and Jean P. Cristol
From the journal

Abstract

Determination of C-reactive protein (CRP) and high-sensitivity CRP (hs-CRP), markers of systemic inflammation and atherosclerosis risk, usually requires serum samples, while heparin plasma samples are routinely collected for routine chemistry. This study evaluates the use of heparin plasma samples for hs-CRP and CRP determinations using immunoturbidimetric methods on an Olympus system. As a result, analytical performance, including linearity, imprecision values, and determination from 185 clinical samples, are not affected by the type of sampling, validating the use of heparin plasma samples for CRP and hs-CRP determination with Olympus reagents.

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Published Online: 2005-06-01
Published in Print: 2003-07-21

Copyright © 2003 by Walter de Gruyter GmbH & Co. KG

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