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Licensed Unlicensed Requires Authentication Published by De Gruyter September 13, 2011

Characterization of phenolic compounds from inner bark of Betula pendula

  • Jaana Liimatainen EMAIL logo , Maarit Karonen , Jari Sinkkonen , Marjo Helander and Juha-Pekka Salminen
From the journal


A method has been developed for the characterization of biologically active silver birch (Betula pendula) inner bark phenolics based on high-performance liquid chromatography/diode array detector (HPLC-DAD)/electrospray ionization-mass spectrometry (ESI-MS). It was demonstrated that the inner bark contains high amounts of flavonoids, arylbutanoids, diarylheptanoids, simple phenolic compounds, phenolic acids, lignans, and procyanidins. Altogether, 30 individual compounds were characterized based on their ultraviolet (UV) and MS data. Structures of 22 compounds were confirmed by nuclear magnetic resonance (NMR) spectroscopy. In addition to previously reported phenolic compounds, 12 compounds were identified in silver birch inner bark for the first time; two of them are novel compounds: 3-β-glucopyranosyloxy-2-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)-propan-1-one and 1,7-bis-(4-hydroxyphenyl)-3-heptanol 3-O-β-ap-iofuranosyl-(1→2)-β-glucopyranoside.

Corresponding author. Laboratory of Organic Chemistry and Chemical Biology, Department of Chemistry, University of Turku, FI-20014, Turku, Finland Phone: +358 2 3336757 Fax: +358 2 2 3336700

Received: 2011-2-7
Accepted: 2011-8-8
Published Online: 2011-09-13
Published in Print: 2012-02-01

©2012 by Walter de Gruyter Berlin Boston

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