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Licensed Unlicensed Requires Authentication Published by De Gruyter June 1, 2005

Treatment of severe cholestasis in neonatal Dubin-Johnson syndrome with ursodeoxycholic acid

R. H. Regev, O. Stolar, A. Raz and T. Dolfin
From the journal

Abstract

We report a case of Dubin-Johnson Syndrome in a neonate presenting with severe direct hyperbilirubinemia, which failed to respond to phenobarbital treatment. Ursodeoxycholic Acid added to therapy was well tolerated, and resulted in declining bilirubin concentration. We suggest ursodeoxycholic acid in treatment for Dubin- Johnson Syndrome with severe direct hyperbilirubinemia presenting in the neonatal age.

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Published Online: 2005-06-01
Published in Print: 2002-04-09

Copyright © 2002 by Walter de Gruyter GmbH & Co. KG

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