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Licensed Unlicensed Requires Authentication Published by De Gruyter July 5, 2017

Epidemiology of Toxoplasma gondii infection in native Tibetans in Tibet, China

Kun Li, Meng Wang, Hui Zhang, Zhixin Lei, Lihong Zhang, Houqiang Luo, Gang Qiu, Khalid Mehmood, Muhammad Shahzad and Jiakui Li
From the journal Acta Parasitologica

Abstract

Toxoplasma gondii (T. gondii) is one of the most common and widespread protozoan parasite which caused toxoplasma infection in animals and humans. Toxoplasma infection in healthy people is usually asymptomatic and it can lead to serious pathological effects in congenital cases and immunodeficient patients. The aim of the study is to investigate the prevalence of T. gondii infection in native Tibetans in Tibet as scarce information is available on such a high plateau. A total of 600 blood samples were collected from Tibetans people who visited the hospital in Nyingchi city with the history of flu, swollen lymph glands, muscle pain, and neurological or eyes complications (showing single or more signs). The serum of collected samples were tested for IgG antibody by ELISA. The result showed that the prevalence in men and women were 11.3% and 11.0%, respectively, the prevalence in different ages were 9.8% in < 7 years, 6.2% in ≥7–17 years, 10.1% in ≥18–40 years, 14.8% in ≥41–65 years and 11.6% in ≥66 years. The current study indicates the first report of this zoonotic parasite infection in Tibetan people.


Kun Li and Meng Wang equally contributed to this paper and should be considered as first co-authors


  1. Conflict of interest The authors declare that they have no competing interests.

Acknowledgments

This study was supported by Key Science Fund of Science and Technology Agency of Tibet Autonomous Region and projects in the National Science & Technology Pillar Program during the 12thFive-year Plan Period (2012BAD3B03).

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Received: 2016-9-30
Revised: 2017-2-25
Accepted: 2017-3-31
Published Online: 2017-7-5
Published in Print: 2017-9-26

© 2017 W. Stefański Institute of Parasitology, PAS

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