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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access March 21, 2015

Proteomic proof that a probiotic elevates glutathione level in human serum

  • Aune Rehema , Tiiu Kullisaar , Kärt Seer , Kristen Reinmann , Mihkel Zilmer and Kalle Kilk
From the journal Open Life Sciences

Abstract

Lactobacillus fermentum ME-3 (LfME-3) has been proven to synthesize and secrete glutathione. A regular use of the foods fermented by it has shown a favourable influence on human lipid profiles and several antioxidant parameters. We administered the LfME-3-fermented kefir for 14 days to 43 human subjects and evaluated their serum with MALDI-TOF mass spectrometer at the beginning and end of the test period. We found an increase of the peak at m/z 308 (corresponding to glutathione) and a new peak at m/z 1467.

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Received: 2013-10-15
Accepted: 2014-5-26
Published Online: 2015-3-21

©2015 Aune Rehema et al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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