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Licensed Unlicensed Requires Authentication Published by De Gruyter November 23, 2016

The multipotent action of electromagnetic field

Natalia Cichoń EMAIL logo , Alicja K. Olejnik , Elzbieta Miller and Joanna Saluk
From the journal Biologia


The use of electromagnetic field in the treatment of diseases has already been known for centuries. Low hazard, wide applicability, good clinical effect and the relatively low cost enable the electromagnetic field therapy to be widely used. The biological effect of the electromagnetic field is based on inter alia, analgesic, anti-inflammatory, osteogenetic and regenerative actions, which are associated with the changes in cellular signal transmission, action on biological membranes, ion transport processes, protein synthesis, cell proliferation and apoptosis. In addition, the electromagnetic field increases quantity of collagen content elevating its density and a more regular arrangement. Furthermore, it induces the activation of glutathione peroxidase and intensification of the process of erythropoiesis leading to better use of oxygen in the tissues around the wound. The electromagnetic field is used in rehabilitation of patients with diseases of skeletal, nervous and respiratory systems. Moreover, electromagnetic field may be used in the course of most inflammatory diseases and in the case of concomitant pain. The objective of this paper is to present the actual state of knowledge on selected applications of electromagnetic field in the biomedical treatment area.





chronic obstructive pulmonary disease


carpal tunnel syndrome


chronic venous insufficiency


extremely low frequency electromagnetic field


forced expiratory volume in 1-second


forced vital capacity


glutathione peroxidase


C-terminal telopeptide of type I collagen


interleukin 1β,2,8,10


mitogen activated protein kinase


monocyte chemoattractant protein-1


maximal expiratory flow


macrophage inflammatory protein 1α


nuclear factor kappa-light-chain-enhancer of activated B cells


platelet activating factor


peak expiratory flow


prostaglandin E2


phosphoinositide 3-kinase


C-terminal propeptide of type I procollagen


N-terminal propeptide of type III procollagen


reactive oxygen species


superoxide dismutase


vascular endothelial growth factor


This study was supported by the Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz (No. 506/1136).


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Received: 2016-5-9
Accepted: 2016-10-17
Published Online: 2016-11-23
Published in Print: 2016-10-1

© 2016 Institute of Molecular Biology, Slovak Academy of Sciences

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