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Licensed Unlicensed Requires Authentication Published by De Gruyter November 23, 2016

The multipotent action of electromagnetic field

Natalia Cichoń EMAIL logo , Alicja K. Olejnik , Elzbieta Miller and Joanna Saluk
From the journal Biologia

Abstract

The use of electromagnetic field in the treatment of diseases has already been known for centuries. Low hazard, wide applicability, good clinical effect and the relatively low cost enable the electromagnetic field therapy to be widely used. The biological effect of the electromagnetic field is based on inter alia, analgesic, anti-inflammatory, osteogenetic and regenerative actions, which are associated with the changes in cellular signal transmission, action on biological membranes, ion transport processes, protein synthesis, cell proliferation and apoptosis. In addition, the electromagnetic field increases quantity of collagen content elevating its density and a more regular arrangement. Furthermore, it induces the activation of glutathione peroxidase and intensification of the process of erythropoiesis leading to better use of oxygen in the tissues around the wound. The electromagnetic field is used in rehabilitation of patients with diseases of skeletal, nervous and respiratory systems. Moreover, electromagnetic field may be used in the course of most inflammatory diseases and in the case of concomitant pain. The objective of this paper is to present the actual state of knowledge on selected applications of electromagnetic field in the biomedical treatment area.

Abbreviations

CAT

catalase

COPD

chronic obstructive pulmonary disease

CTS

carpal tunnel syndrome

CVI

chronic venous insufficiency

ELF-EMF

extremely low frequency electromagnetic field

FEV1

forced expiratory volume in 1-second

FVC

forced vital capacity

GPx

glutathione peroxidase

ICTP

C-terminal telopeptide of type I collagen

IL-1β,2,8,10

interleukin 1β,2,8,10

MAPK

mitogen activated protein kinase

MCP-1/CCL2

monocyte chemoattractant protein-1

MEF75

maximal expiratory flow

MIP1α

macrophage inflammatory protein 1α

NFκB

nuclear factor kappa-light-chain-enhancer of activated B cells

PAF

platelet activating factor

PEF

peak expiratory flow

PGE2

prostaglandin E2

PI3K

phosphoinositide 3-kinase

PICP

C-terminal propeptide of type I procollagen

PIIINP

N-terminal propeptide of type III procollagen

ROS

reactive oxygen species

SOD

superoxide dismutase

VEGF

vascular endothelial growth factor

Acknowledgements

This study was supported by the Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz (No. 506/1136).

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Received: 2016-5-9
Accepted: 2016-10-17
Published Online: 2016-11-23
Published in Print: 2016-10-1

© 2016 Institute of Molecular Biology, Slovak Academy of Sciences

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