Abstract
In this study, breast cancer classification as benign or malignant was made using images obtained by histopathological procedures, one of the medical imaging techniques. First of all, different noise types and several intensities were added to the images in the used data set. Then, the noise in images was removed by applying the Wavelet Transform (WT) process to noisy images. The performance rates in the denoising process were found out by evaluating Peak Signal to Noise Rate (PSNR) values of the images. The Gaussian noise type gave better results than other noise types considering PSNR values. The best PSNR values were carried out with the Gaussian noise type. After that, the denoised images were classified by Convolution Neural Network (CNN), one of the deep learning techniques. In this classification process, the proposed CNN model and the VggNet-16 model were used. According to the classification result, better results were obtained with the proposed CNN model than VggNet-16. The best performance (86.9%) was obtained from the data set created Gaussian noise with 0.3 noise intensity.
-
Research funding: None declared.
-
Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
-
Competing interests: Authors state no conflict of interest.
-
Informed consent: Informed consent was obtained from all individuals included in this study.
-
Ethical approval: No ethical approval is required for this study.
References
1. Topuz, E, Aydıner, A, Dincer, M. Meme Kanseri, 1st ed. Ankara, Turkey: Nobel Tıp Kitabevi; 2003.Search in Google Scholar
2. Baldi, V, Cicalese, A, Coppala, G, Scarano, M, Gatto, E. Results of mammographic screening 1994–1997. Eur J Cancer 2003;34. https://doi.org/10.1016/S0959-8049(98)80388-2.Search in Google Scholar
3. Jadoon, MM, Zhang, Q, Haq, IU, Butt, S, Jadoon, A. Three-class mammogram classification based on descriptive CNN features. BioMed Res Int 2017;3640901:1–11. https://doi.org/10.1155/2017/3640901.Search in Google Scholar
4. Houssein, EH, Emam, MM, Ali, AA, Suganthan, PN. Deep and machine learning techniques for medical imaging-based breast cancer: a comprehensive review. Expert Syst Appl 2021;167:114161.10.1016/j.eswa.2020.114161Search in Google Scholar
5. Kopans, DB, Feig, SA. The Canadian National Breast Cancer Screening Study 1993;161:755–60. https://doi.org/10.2214/ajr.161.4.8372752.Search in Google Scholar
6. Sites, A. SEER cancer statistics review 1975–2011. Maryland, USA: National Cancer Institute; 2012.Search in Google Scholar
7. Kelek, MM, Cengiz, E, Oğuz, Y, Yönetken, A. Examination and classification of mammography images with the RLBP method. AKU-IJETAS 2021;4:59–64. https://doi.org/10.53448/akuumubd.978181.Search in Google Scholar
8. Smith, RA, von Eschenbach, AC, Wender, R, Levin, B, Byers, T, Rothenberger, D, et al.. American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers: also: update 2001—testing for early lung cancer detection. CA A Cancer J Clin 2001;51:38–75. https://doi.org/10.3322/canjclin.51.1.38.Search in Google Scholar
9. Holland, T. So-called interval cancers of the breast: pathologic and radiographic analysis. Cancer 1982;49:2527–33. https://doi.org/10.1002/1097-0142(19820615)49:12<2527::aid-cncr2820491220>3.0.co;2-e.10.1002/1097-0142(19820615)49:12<2527::AID-CNCR2820491220>3.0.CO;2-ESearch in Google Scholar
10. Brzakovic, D, Neskovic, M. Mammogram screening using multiresolution-based image segmentation. Int J Pattern Recogn Artif Intell 1993;7:1437–60. https://doi.org/10.1142/s0218001493000704.Search in Google Scholar
11. Tiryaki, V. Mamografi görüntülerindeki anormalliklerin yerel ikili örüntü ve varyantları kullanılarak sınıflandırılması. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 2020;9:297–305.10.17798/bitlisfen.557411Search in Google Scholar
12. Alpaslan, N, Toptaş, M, Öztürk, B, Hanbay, D. Mamografi İmgelerimdeki Kitle Tespiti ve Normal-İyi-Kötü Huylu Ayırımı. Turkey: TIPTEKNO Kapodokya; 2014:160–257 pp.Search in Google Scholar
13. Işeri̇, I. An artificial intelligence based software application for microcalcification detection on mammogram images. 24th SIU Zonguldak, Turkey; 2016:1973–6 pp.10.1109/SIU.2016.7496154Search in Google Scholar
14. Yengeç Taşdemir, S, Taşdemir, K, Aydın, Z. Ysa Kullanılarak Mamogramlardan Dokusal Öznitelik Tabanlı Meme Kanseri İlgi Bölgesi Tespiti. Mühendislik Bilimleri ve Tasarım Dergisi, Special Issue: ICAIAME 2020; 2020:133–41 pp.10.21923/jesd.827131Search in Google Scholar
15. Şentürk Karapınar, Z, Şentürk, A. Yapay Sinir ağları ile Göğüs Kanseri Tahmini. ECJSE 2016;3:345–50.Search in Google Scholar
16. Solak, A, Ceylan, R. Classification of mammography images by transfer learning. 28th SIU Gaziantep, Turkey; 2020:1545–8 pp. https://doi.org/10.1109/siu49456.2020.9302323.Search in Google Scholar
17. Alpaslan, N. Meme Kanseri Tanısı İçin Derin Öznitelik Tabanlı Karar Destek Sistemi. SUJEST 2019;7:213–27. https://doi.org/10.15317/scitech.2019.193.Search in Google Scholar
18. Narin, A. Meme Kanserinin Evrişimsel Sinir Ağı Modelleriyle Tespitinde Farklı Görüntü Büyütme Oranlarının Etkisi. Karaelmas Sci Eng J. 2020;10:186–94.Search in Google Scholar
19. Talo, M. Meme Kanseri Histopatalojik Görüntülerinin Konvolüsyonal Sinir ağları ile Sınıflandırılması. FÜMBD 2019;31:391–8. https://doi.org/10.35234/fumbd.517939.Search in Google Scholar
20. Spanhol, F, Oliveira, E, Petitjean, C, Heutte, L. Breast cancer histopathological image classification using convolutional neural networks. IJCNN 2016;32:2560–7. https://doi.org/10.1109/ijcnn.2016.7727519.Search in Google Scholar
21. Kahya, A, Al-Hayani, W, Algamal, Y. Classification of breast cancer histopathology images based on adaptive sparse support vector machine. J Appl Math Bioinf 2017;7:49–56.Search in Google Scholar
22. Belsare, AD, Mushrif, MM, Pangarkar, MA, Meshram, N. Classification of breast cancer histopathology images using texture feature analysis. TENCON Conf. 2015. https://doi.org/10.1109/tencon.2015.7372809.Search in Google Scholar
23. Cireşan, DC, Giusti, A, Gambardella, LM, Schmidhuber, J. Mitosis detection in breast cancer histology images with deep neural networks, Med Image Comput Comput Assist Interv: Berlin, Heidelberg; 2013:411–8 pp.10.1007/978-3-642-40763-5_51Search in Google Scholar PubMed
24. Yang, X, Yeo, SY, Hong, JM, Wong, ST, Tang, WT, Wu, ZZ, et al.. A deep learning approach for tumor tissue image classification. Proc. 12nd IASTED Int. Conf. Biomed. Eng. BioMed 2016. https://doi.org/10.2316/P.2016.832-025.Search in Google Scholar
25. Vaka, AR, Soni, B, Reddy, S. Breast cancer detection by leveraging machine learning. ICT Express 2020;6:320–4.https://doi.org/10.1016/j.icte.2020.04.009.Search in Google Scholar
26. Kivanc Mihcak, M, Kozintsev, I, Ramchandran, K, Moulin, P. Low-complexity image denoising based on statistical modeling of wavelet coefficients. IEEE Signal Process Lett 1999;6:300–3. https://doi.org/10.1109/97.803428.Search in Google Scholar
27. Chang, SG, Bin Yu Vetterli, M. Adaptive wavelet thresholding for image denoising and compression. IEEE Trans Image Process 2000;9:1532–46.https://doi.org/10.1109/83.862633.Search in Google Scholar
28. Ruikar, SD, Doye, DD. Wavelet based image denoising technique. Int J Adv Comput Sci Appl 2011;2:49–53.Search in Google Scholar
29. Smith, CB, Agaian, S, Akopian, D. A wavelet-denoising approach using polynomial threshold operators. IEEE Signal Process Lett 2008;15:906–9. https://doi.org/10.1109/lsp.2008.2001815.Search in Google Scholar
30. Luisier, F, Blu, T, Unser, M. A new sure approach to image denoising: interscale orthonormal wavelet thresholding. IEEE Trans Image Process 2007;16:593–606. https://doi.org/10.1109/tip.2007.891064.Search in Google Scholar
31. Chen, GY, Bui, TD, Krzyzak, A. Image denoising using neighbouring wavelet coefficients. Integrated Comput Aided Eng 2005;12:99–107. https://doi.org/10.3233/ica-2005-12108.Search in Google Scholar
32. Messer, SR, Agzarian, J, Abbott, D. Optimal wavelet denoising for phonocardiograms. Microelectron J 2001;32:931–41. https://doi.org/10.1016/s0026-2692(01)00095-7.Search in Google Scholar
33. Alfaouri, M, Daqrouq, K. ECG signal denoising by wavelet transform thresholding. Am J Appl Sci 2008;5:276–81. https://doi.org/10.3844/ajassp.2008.276.281.Search in Google Scholar
34. Mencattini, A, Salmeri, M, Lojacono, R, Frigerio, M, Caselli, F. Mammographic images enhancement and denoising for breast cancer detection using dyadic wavelet processing. IEEE Trans Instrum Meas 2008;57:1422–30. https://doi.org/10.1109/tim.2007.915470.Search in Google Scholar
35. Gorgel, P, Sertbas, A, Ucan, ON. A wavelet-based mammographic image denoising and enhancement with Homomorphic filtering. J Med Syst 2010;34:993–1002. https://doi.org/10.1007/s10916-009-9316-3.Search in Google Scholar PubMed
36. Aarthy, SL, Prabu, S. An approach for detecting breast cancer using wavelet transforms. Indian J Sci Technol 2015;8:1–7. https://doi.org/10.17485/ijst/2015/v8i26/81600.Search in Google Scholar
37. Rasheed, A, Younis, MS, Qadir, J, Bilal, M. Use of transfer learning and wavelet transform for breast cancer detection. arXiv preprint arXiv:2103.03602; 2021.Search in Google Scholar
38. Dabass, J, Dabass, M., Edge correction, and enhancement of breast cancer ultrasound images. Advances in Communication and Computational Technology. Lect Notes Electr Eng 2020;1153–72. Springer, Singapore.10.1007/978-981-15-5341-7_88Search in Google Scholar
39. de Santana, MA, Pereira, JMS, da Silva, WWA, dos Santos, WP. Breast cancer diagnosis in mammograms using wavelet analysis, Haralick descriptors, and autoencoder. AI Innovat Med Imaging Diagn 2021;1:76–91. https://doi.org/10.4018/978-1-7998-3092-4.ch004.Search in Google Scholar
40. Grossman, A, Morlet, J. Decomposition of Hardy functions into square integrable wavelets of constant shape. SIAM J Math Anal 1984;15:723–36. https://doi.org/10.1137/0515056.Search in Google Scholar
41. Haşiloğlu, A. Dalgacık dönüşümü ve yapay sinir ağları ile döndürmeye duyarsız doku analizi ve sınıflandırma. Turk J Eng Environ Sci 2001;25:405–13.Search in Google Scholar
42. Öner, İV, Yeşilyurt, MK, Yılmaz, EÇ. Wavelet Analiz Tekniği ve Uygulama Alanları. Ordu Univ Bilim Teknol Derg 2017;7:42–56.Search in Google Scholar
43. Breast Histopathology Images. Available from: https://www.kaggle.com/paultimothymooney/breast-histopathology-images#IDC_regular_ps50_idx5.zip [Accessed 1 Nov 2021].Search in Google Scholar
44. Buduma, N, Locascio, N. Fundamentals of deep learning: designing next-generation machine intelligence algorithms. California, USA: O’Reilly Media Inc.; 2017.Search in Google Scholar
45. Cengiz, E, Yilmaz, C, Kahraman, H. Classification of human and vehicles with the deep learning based on transfer learning method. Duzce University J Sci Technol 2021;9:215–25.10.29130/dubited.842394Search in Google Scholar
46. Cengiz, E, Yılmaz, C, Kahraman, HT, Bayram, F. Pedestrian and vehicles detection with ResNet in aerial images. In: 4th international symposium on innovative approaches in engineering and natural sciences, Samsun, Turkey; 2019:416–9 pp. https://doi.org/10.36287/setsci.4.6.107.Search in Google Scholar
47. Zeng, Y, Zhang, J. A machine learning model for detecting invasive ductal carcinoma with Google Cloud AutoML Vision. Comput Biol Med 2020;122:1–8. https://doi.org/10.1016/j.compbiomed.2020.103861.Search in Google Scholar PubMed
48. Alghodhaifi, H, Alghodhaifi, A, Alghodhaifi, M. Predicting invasive ductal carcinoma in breast histology images using convolutional neural network. NAECON 2019;1:374–8. https://doi.org/10.1109/naecon46414.2019.9057822.Search in Google Scholar
49. Reza, MS, Ma, J. Imbalanced histopathological breast cancer image classification with convolutional neural network. 14th ICSP Conf. 2018. https://doi.org/10.1109/icsp.2018.8652304.Search in Google Scholar
50. Abdolahi, M, Salehi, M, Shokatian, I, Reiazi, R. Artificial intelligence in automatic classification of invasive ductal carcinoma breast cancer in digital pathology images. MJIRI 2020;34:1–9. https://doi.org/10.47176/mjiri.34.140.Search in Google Scholar
© 2022 Walter de Gruyter GmbH, Berlin/Boston