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Licensed Unlicensed Requires Authentication Published by De Gruyter September 20, 2014

MR-visualization of surgical textile implants

  • Jens Otto EMAIL logo , Nicolas Kuehnert , Daniel Busch , Andreas Lambertz , Christian Klink , Nienke L. Hansen , Alexander Ciritsis , Christiane Kuhl , Uwe Klinge , Ulf Peter Neumann , Joachim Conze and Nils A. Kraemer
From the journal BioNanoMaterials


The use of surgical textile implants (so-called “mesh”) for hernia repair is an accepted standard. They may cause mesh-related problems such as chronic pain, migration or fistula formation. Nevertheless, these polymer-based textile meshes are often invisible by conventional imaging methods like computed tomography (CT) and magnetic resonance imaging (MRI). In this study we outlined the major steps in the development of a MR-visible textile implant, which can be used in patients. To achieve MR-visability, ferrooxide particles were incorporated into the base material polyvinylidene fluoride (PVDF), during the spinning process. We could proof the MR-visibility of this new textile implant in different phantoms. After clinical approval of these implants in vivo in different animal studies, we pursued to evaluate the MR-conspicuity of such ferrooxide-loaded mesh implants in patients treated for inguinal hernias and explored the postsurgical mesh configuration by MRI. In this study we described the development and first results of a ferrooxide-loaded MR-visible mesh. In animal model and in clinical use such implants turned out to be a valuable tool for diagnostic and development.

Corresponding author: Dr. Jens Otto, Department of General, Visceral and Transplant Surgery, University Hospital, RWTH Aachen University, 52074 Aachen, Germany, Phone: +49 241 8089500, E-mail:
aJoachim Conze and Nils Kraemer contributed equally for last authorship.


This project was supported by the German Federal Ministry of Education and Research (Ref. 01 EZ 0849) and the German Federal Ministry of Economics and Technology (Support Code KF2545603AJ1).


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Received: 2014-4-7
Accepted: 2014-8-22
Published Online: 2014-9-20
Published in Print: 2014-9-1

©2014 by De Gruyter

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