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Licensed Unlicensed Requires Authentication Published by De Gruyter February 22, 2014

Method-specific differences in β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen and procollagen type I amino-terminal propeptide using two fully automated immunoassays

  • Gillian Wheater EMAIL logo , Cheryl Goodrum , Stephen P. Tuck , Harish K. Datta and Jacob M. van Laar

Corresponding author: Gillian Wheater, Department of Biochemistry, The James Cook University Hospital, Middlesbrough, Cleveland, TS4 3BW, UK, Phone: +44 1642 835870, E-mail: ; and Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK


The authors wish to thank staff and volunteers from the Pathology and Rheumatology departments at the James Cook University Hospital, Middlesbrough who made this study possible. We thank Immuno-Diagnostic Systems (Boldon, UK) for providing PINP and βCTX reagents for the iSYS analyser.

Conflict of interest statement

Authors’ conflict of interest disclosure: The authors stated that there are no conflicts of interest regarding the publication of this article. Research support played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

Research funding: None declared.

Employment or leadership: JMvL has received a research grant, consultancy and speaker fees from Roche. SPT has received speaker fees from Ely Lilly.

Honorarium: None declared.


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Received: 2013-10-29
Accepted: 2014-1-31
Published Online: 2014-2-22
Published in Print: 2014-7-1

©2014 by Walter de Gruyter Berlin/Boston

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