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Licensed Unlicensed Requires Authentication Published by De Gruyter May 15, 2014

Red blood cell distribution width is significantly associated with aging and gender

  • Giuseppe Lippi EMAIL logo , Gian Luca Salvagno and Gian Cesare Guidi

Corresponding author: Prof. Giuseppe Lippi, U.O. Diagnostica Ematochimica, Azienda Ospedaliero-Universitaria di Parma, Via Gramsci, 14, 43126 Parma, Italy, Phone: +39 0521 703050/ +39 0521 703791, E-mail: ;

Conflict of interest statement

Authors’ conflict of interest disclosure: The authors stated that there are no conflicts of interest regarding the publication of this article.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.


1. Montagnana M, Cervellin G, Meschi T, Lippi G. The role of red blood cell distribution width in cardiovascular and thrombotic disorders. Clin Chem Lab Med 2011;50:635–41.Search in Google Scholar

2. Patel KV, Semba RD, Ferrucci L, Newman AB, Fried LP, Wallace RB, et al. Red cell distribution width and mortality in older adults: a meta-analysis. J Gerontol A Biol Sci Med Sci 2010;65:258–65.10.1093/gerona/glp163Search in Google Scholar PubMed PubMed Central

3. Di Somma S, Magrini L, Travaglino F, Lalle I, Fiotti N, Cervellin G, et al. Opinion paper on innovative approach of biomarkers for infectious diseases and sepsis management in the emergency department. Clin Chem Lab Med 2013;51:1167–75.10.1515/cclm-2012-0795Search in Google Scholar PubMed

4. Hu Z, Sun Y, Wang Q, Han Z, Huang Y, Liu X, et al. Red blood cell distribution width is a potential prognostic index for liver disease. Clin Chem Lab Med 2013;51:1403–8.10.1515/cclm-2012-0704Search in Google Scholar PubMed

5. Lippi G, Cervellin G. Risk assessment of post-infarction heart failure. Systematic review on the role of emerging biomarkers. Crit Rev Clin Lab Sci 2014;51:13–29.10.3109/10408363.2013.863267Search in Google Scholar PubMed

6. Xi Q, Wang Y, Liu Z, Zhao Z, Luo Q. Red cell distribution width predicts chronic thromboembolic pulmonary hypertension in patients with acute pulmonary embolism in a long-term follow-up. Clin Chem Lab Med 2014;52:e191–5.10.1515/cclm-2014-0092Search in Google Scholar PubMed

7. Qiao R, Yang S, Yao B, Wang H, Zhang J, Shang H. Complete blood count reference intervals and age- and sex-related trends of North China Han population. Clin Chem Lab Med 2014;52:1025–32.10.1515/cclm-2012-0486Search in Google Scholar PubMed

8. Lippi G, Targher G, Montagnana M, Salvagno GL, Zoppini G, Guidi GC. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med 2009;133:628–32.10.5858/133.4.628Search in Google Scholar PubMed

9. Lippi G, Sanchis-Gomar F, Montagnana M. Biological markers in older people at risk of mobility limitations. Curr Pharm Des [Epub ahead of print 18 Sep 2013].Search in Google Scholar

10. Patel KV, Mohanty JG, Kanapuru B, Hesdorffer C, Ershler WB, Rifkind JM. Association of the red cell distribution width with red blood cell deformability. Adv Exp Med Biol 2013;765: 211–6.10.1007/978-1-4614-4989-8_29Search in Google Scholar PubMed PubMed Central

Received: 2014-4-1
Accepted: 2014-4-6
Published Online: 2014-5-15
Published in Print: 2014-9-1

©2014 by De Gruyter

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