Accessible Unlicensed Requires Authentication Published by De Gruyter March 14, 2015

Laboratory biomarkers and frailty: presentation of the FRAILOMIC initiative

Giuseppe Lippi ORCID logo, Pidder Jansen-Duerr, Jose Viña, Anna Durrance-Bagale, Imad Abugessaisa, David Gomez-Cabrero, Jesper Tegnér, Johannes Grillari, Jorge Erusalimsky, Alan Sinclair, Leocadio Rodriguez-Manãs and on behalf of the FRAILOMIC consortium

Corresponding author: Prof. Giuseppe Lippi, U.O. Diagnostica Ematochimica, Azienda Ospedaliero-Universitaria di Parma, Via Gramsci 14, 43126 Parma, Italy, Phone: +39 0521 703050, Fax: +39 0521 703791, E-mail: ; .


1. Rodríguez-Mañas L, Sinclair AJ. Frailty: the quest for new domains, clinical definitions and subtypes. Is this justified on new evidence emerging? J Nutr Health Aging 2014;18:92–4.Search in Google Scholar

2. Rodríguez-Artalejo F, Rodríguez-Mañas L. The frailty syndrome in the public health agenda. J Epidemiol Community Health 2014;68:703–4.Search in Google Scholar

3. Laosa O, Alonso C, Castro M, Rodriguez-Manas L. Pharmaceutical interventions for frailty and sarcopenia. Curr Pharm Des 2014;20:3068–82.Search in Google Scholar

4. Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet 2013;381:752–62.Search in Google Scholar

5. Lippi G, Plebani M. Biomarker research and leading causes of death worldwide: a rather feeble relationship. Clin Chem Lab Med 2013;51:1691–3.Search in Google Scholar

6. Plebani M. From symptoms to biomarkers: a change of paradigm. Clin Chem Lab Med 2014;52:1513–5.Search in Google Scholar

7. Lippi G, Sanchis-Gomar F, Montagnana M. Biological markers in older people at risk of mobility limitations. Curr Pharm Des 2014;20:3222–44.Search in Google Scholar

8. Fernández-Garrido J, Ruiz-Ros V, Buigues C, Navarro-Martinez R, Cauli O. Clinical features of prefrail older individuals and emerging peripheral biomarkers: a systematic review. Arch Gerontol Geriatr 2014;59:7–17.Search in Google Scholar

9. Plebani M. Harmonization in laboratory medicine: the complete picture. Clin Chem Lab Med 2013;51:741–51.Search in Google Scholar

10. Hens K, Berth M, Armbruster D, Westgard S. Sigma metrics used to assess analytical quality of clinical chemistry assays: importance of the allowable total error (TEa) target. Clin Chem Lab Med 2014;52:973–80.Search in Google Scholar

Received: 2015-2-11
Accepted: 2015-2-18
Published Online: 2015-3-14
Published in Print: 2015-9-1

©2015 by De Gruyter