We sincerely thank Abbott Diagnostics for providing the hs-cTnI kits. The authors also acknowledge the laboratory assistance of V.W.V.C. Kleijnen. This work was supported by a research grant from Stichting De Weijerhorst to M.P v.D-V.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Financial support: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
1. Apple FS, Murakami MM, Pearce LA, Herzog CA. Multi-biomarker risk stratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death. Clin Chem 2004;50:2279–85. Search in Google Scholar
2. Mishra RK, Li Y, DeFilippi C, Fischer MJ, Yang W, Keane M, et al. Association of cardiac troponin T with left ventricular structure and function in CKD. Am J Kidney Dis 2013;61:701–9. Search in Google Scholar
3. deFilippi C, Seliger SL, Kelley W, Duh SH, Hise M, Christenson RH, et al. Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome. Clin Chem 2012;58:1342–51. Search in Google Scholar
4. Wahl HG, Graf S, Renz H, Fassbinder W. Elimination of the cardiac natriuretic peptides B-type natriuretic peptide (BNP) and N-terminal proBNP by hemodialysis. Clin Chem 2004;50:1071–4. Search in Google Scholar
5. Sommerer C, Heckele S, Schwenger V, Katus HA, Giannitsis E, Zeier M. Cardiac biomarkers are influenced by dialysis characteristics. Clin Nephrol 2007;68:392–400. Search in Google Scholar
6. Hassan HC, Howlin K, Jefferys A, Spicer ST, Aravindan AN, Suryanarayanan G, et al. High-sensitivity troponin as a predictor of cardiac events and mortality in the stable dialysis population. Clin Chem 2014;60:389–98. Search in Google Scholar
7. Assa S, Gansevoort RT, Westerhuis R, Kobold AC, Voors AA, de Jong PE, et al. Determinants and prognostic significance of an intra-dialysis rise of cardiac troponin I measured by sensitive assay in hemodialysis patients. Clin Res Cardiol 2013;102:439–45. Search in Google Scholar
8. Lippi G, Tessitore N, Montagnana M, Salvagno GL, Lupo A, Guidi GC. Influence of sampling time and ultrafiltration coefficient of the dialysis membrane on cardiac troponin I and T. Arch Pathol Lab Med 2008;132:72–6. Search in Google Scholar
9. Cornelis T, van der Sande FM, Eloot S, Cardinaels E, Bekers O, Damoiseaux J, et al. Acute hemodynamic response and uremic toxin removal in conventional and extended hemodialysis and hemodiafiltration: a randomized crossover study. Am J Kidney Dis 2014;64:247–56. Search in Google Scholar
10. Klinkenberg LJ, van Dijk JW, Tan FE, van Loon LJ, van Dieijen-Visser MP, Meex SJ. Circulating cardiac troponin T exhibits a diurnal rhythm. J Am Coll Cardiol 2014;63:1788–95. Search in Google Scholar
©2015 by De Gruyter