Accessible Requires Authentication Published by De Gruyter September 24, 2015

Practical approach for medical validation of therapeutic drug monitoring results

Matthijs Oyaert, Inger Brandt, Pieter Vermeersch, Koenraad Desmet, Florent Vanstapel and Steven Pauwels

Corresponding author: Matthijs Oyaert, Department of Laboratory Medicine, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium, Phone: +32 16 34 70 00, Fax: +32 16 34 79 31, E-mail:

References

1. Valdiguié PM, Rogari E, Philippe H. VALAB: expert system for validation of biochemical data. Clin Chem 1992;38:83–7. Search in Google Scholar

2. Oosterhuis WP, Ulenkare H, Goldschmidt H. Evaluation of LabRespond, a new automated validation system for clinical Laboratory test results. Clin Chem 2000;46:1811–7. Search in Google Scholar

3. Pauwels S, Vermeersch P, Desmet K, Vanstapel F. Practice-oriented quality specifications for therapeutic drug monitoring. Clin Chem 2014;60:559–60. Search in Google Scholar

4. Tukey JW. Exploratory data analysis. Reading, MA: Addison-Wesley, 1977. Search in Google Scholar

5. Pauwels S, Peersman N, Gerits M, Desmet K, Vermeersch P. Response factor-based quantification for mycophenolic acid. Clin Chem 2014;60:692–4. Search in Google Scholar

6. Pauwels S, Jans I, Peersman N, Billen J, Vanderschueren D, Desmet K, et al. Possibilities and limitations of signal summing for an immunosuppressant LC-MS/MS method. Anal Bioanal Chem 2015;407:6191–9. Search in Google Scholar

7. Pauwels S, Vermeersch P, Van Eldere J, Desmet K. Fast and simple LC-MS/MS method for quantifying plasma voriconazole. Clin Chim Acta 2012;413:740–3. Search in Google Scholar

8. CLSI. Evaluation of precision performance of quantative measurement method; approved guideline, 2nd ed. Wayne (PA): CLSI Document EP05-A2. Wayne, PA: Clinical Laboratory Institute, 2004. Search in Google Scholar

9. Fraser CG. Reference changed values. Clin Chem Lab Med 2012;50:807–12. Search in Google Scholar

Received: 2015-7-10
Accepted: 2015-8-26
Published Online: 2015-9-24
Published in Print: 2016-3-1

©2016 by De Gruyter