We would like to thank Dr. Bindhu Nair for helping with the compiling of the references.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: The authors gratefully acknowledge the financial support received for this research from the Medical Research Council of Ireland, the Department of Education, and the National University of Ireland Galway (Postgraduate Fellowship).
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organisation(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
Ethical approval: The research work was carried out in the Physiology laboratories at the National University of Ireland Galway (NUIG). A permit to import the animals for the research work from the UK was obtained from the Department of Agriculture (Veterinary Section), Kildare St., Dublin 2, Ireland. A license to undertake the animal experiments was granted by the Department of Health (Public Health Division), Hawkins House, Dublin 2, Ireland.
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