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Licensed Unlicensed Requires Authentication Published by De Gruyter August 29, 2018

Procalcitonin as guide to therapy in endovascular infections: caveat emptor!

Martina Spaziante, Giancarlo Ceccarelli ORCID logo and Mario Venditti

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


1. Bartoletti M, Antonelli M, Bruno Blasi FA, Casagranda I, Chieregato A, Fumagalli R, et al. Procalcitonin-guided antibiotic therapy: an expert consensus. Clin Chem Lab Med 2018;56: 1223–9.10.1515/cclm-2018-0259Search in Google Scholar

2. Yan ST, Sun LC, Jia HB, Gao W, Yang JP, Zhang GQ. Procalcitonin levels in bloodstream infections caused by different sources and species of bacteria. Am J Emerg Med 2017;35:579–83.10.1016/j.ajem.2016.12.017Search in Google Scholar

3. Ceccarelli G, Giuliano S, Falcone M, Venditti M. Follow-up blood cultures: a 2.0 diagnostic tool in patients with Gram-negative bacteremia and septic thrombophlebitis. Clin Infect Dis 2018;66:1154–5.10.1093/cid/cix949Search in Google Scholar

4. Spaziante M, Ceccarelli G, Al Moghazi S, Alessandri F, Venditti M. Specific dynamic of serum procalcitonin in critically ill patients affected by Gram-negative bacilli septic thrombophlebitis. Crit Care 2018;22:178.10.1186/s13054-018-2116-8Search in Google Scholar

5. Iacovelli A, Spaziante M, Al Moghazi S, Giordano A, Ceccarelli G, Venditti M. A challenging case of carbapenemase-producing Klebsiella pneumoniae septic thrombophlebitis and right mural endocarditis successfully treated with ceftazidime/avibactam. Infection 2018. doi: 10.1007/s15010-018-1166-9. [Epub ahead of print] Erratum in: Infection. 2018 Jul 10.10.1007/s15010-018-1166-9Search in Google Scholar

6. Ayres JS, Schneider DS. Two ways to survive an infection: what resistance and tolerance can teach us about treatments for infectious diseases. Nat Rev Immunol 2008;8:889–95.10.1038/nri2432Search in Google Scholar

Received: 2018-06-22
Accepted: 2018-07-25
Published Online: 2018-08-29
Published in Print: 2019-03-26

©2019 Walter de Gruyter GmbH, Berlin/Boston