Acknowledgments
Beckman Coulter, Korea supplied all reagents and calibrators used in this study.
Author contributions: This study was designed and organized by SM Lee, KR Jun, and HH Kim. SY Moon wrote the first draft and performed statistical analysis. N Kim, SM Lee, S Yu, and KR Jun reviewed participants’ health check-up results and decided which individuals to include. The final manuscript was reviewed, edited, and approved by all authors. All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: HH Kim, KR Jun, and SM Lee received additional research funding for this study from Beckman Coulter, Korea.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
References
1. Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J 2019;40:237–69.10.1093/eurheartj/ehy462Search in Google Scholar
2. Apple FS, Jaffe AS, Collinson P, Mockel M, Ordonez-Llanos J, Lindahl B, et al. IFCC educational materials on selected analytical and clinical applications of high sensitivity cardiac troponin assays. Clin Biochem 2015;48:201–3.10.1016/j.clinbiochem.2014.08.021Search in Google Scholar
3. Clerico A, Zaninotto M, Ripoli A, Masotti S, Prontera C, Passino C, et al. The 99th percentile of reference population for cTnI and cTnT assay: methodology, pathophysiology and clinical implications. Clin Chem Lab Med 2017;55:1634–51.10.1515/cclm-2016-0933Search in Google Scholar
4. Moretti M, Pieretti B, Sisti D, Rocchi M, Gasperoni S. Analytical performance and clinical decision limit of a new release for cardiac troponin I assay. Ann Clin Biochem 2015;52:169–72.10.1177/0004563214529749Search in Google Scholar
5. Greene DN, Leong TK, Collinson PO, Kamer SM, Huang K, Lorey TS, et al. Age, sex, and racial influences on the Beckman Coulter AccuTnI+3 99th percentile. Clin Chim Acta. 2015;444:149–53.10.1016/j.cca.2015.02.005Search in Google Scholar
6. Ungerer JP, Tate JR, Pretorius CJ. Discordance with 3 cardiac troponin i and T assays: implications for the 99th percentile cutoff. Clin Chem 2016;62:1106–14.10.1373/clinchem.2016.255281Search in Google Scholar
7. Pretorius CJ, Tate JR, Wilgen U, Cullen L, Ungerer JP. A critical evaluation of the Beckman Coulter Access hsTnI: analytical performance, reference interval and concordance. Clin Biochem 2018;55:49–55.10.1016/j.clinbiochem.2018.03.003Search in Google Scholar
8. Ko DH, Jeong TD, Cho EJ, Lim J, Ji M, Lee K, et al. The 99th percentile values of six cardiac troponin assays established for a reference population using strict selection criteria. Clin Chim Acta 2017;464:1–5.10.1016/j.cca.2016.11.004Search in Google Scholar
9. Horn PS, Pesce AJ. Reference intervals: an update. Clin Chim Acta 2003;334:5–23.10.1016/S0009-8981(03)00133-5Search in Google Scholar
©2019 Walter de Gruyter GmbH, Berlin/Boston
