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Licensed Unlicensed Requires Authentication Published by De Gruyter January 13, 2020

New insights on the analytical performances for detecting and quantifying monoclonal proteins

Mario Plebani ORCID logo EMAIL logo
  1. Author contributions: The author has accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

References

1. Willrich MA, Katzmann JA. Laboratory testing requirements for diagnosis and follow-up of multiple myeloma and related plasma cell dyscrasias. Clin Chem Lab Med 2016;54:907–19.10.1515/cclm-2015-0580Search in Google Scholar PubMed

2. Keren DF, Schroeder L. Challenges of measuring monoclonal proteins in serum. Clin Chem Lab Med 2016;54:947–61.10.1515/cclm-2015-0862Search in Google Scholar PubMed

3. Dimopoulos M, Kyle R, Fermand JP, Rajkumar SV, San Miguel J, Chanan-Khan A, et al. Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3. Blood 2011;117:4701–5.10.1182/blood-2010-10-299529Search in Google Scholar PubMed

4. Tate JR, Keren DF, Mollee P. A global call to arms for clinical laboratories – harmonised quantification and reporting of monoclonal proteins. Clin Biochem 2018;51:4–9.10.1016/j.clinbiochem.2017.11.009Search in Google Scholar PubMed

5. Turner KA, Frinack JL, Ettore MW, Tate JR, Graziani MS, Jacobs JF, et al. An international multi-center serum protein electrophoresis accuracy and M-protein isotyping study. Part I: factors impacting limit of quantitation of serum protein electrophoresis. Clin Chem Lab Med 2020;58:533–46.10.1515/cclm-2019-1104Search in Google Scholar PubMed

6. Jacobs JF, Turner KA, Graziani MS, Frinack JL, Ettore MW, Tate JR, et al. An international multi-center serum protein electrophoresis accuracy and M-protein isotyping study. Part II: limit of detection and follow-up of patients with small M-proteins. Clin Chem Lab Med 2020;58:547–59.10.1515/cclm-2019-1105Search in Google Scholar PubMed

7. Rajkumar SV, Harousseau JL, Durie B, Anderson KC, Dimopoulos M, Kyle R, et al. Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1. Blood 2011;117:4691–5.10.1182/blood-2010-10-299487Search in Google Scholar PubMed PubMed Central

8. Plebani M. Clinical laboratories: bigger is not always better. Diagnosis (Berlin) 2018;5:41–6.10.1515/dx-2018-0019Search in Google Scholar PubMed

9. Plebani M. Quality and future of clinical laboratories: the Vico’s whole cyclical theory of the recurring cycles. Clin Chem Lab Med 2018;56:901–8.10.1515/cclm-2018-0009Search in Google Scholar PubMed

Published Online: 2020-01-13
Published in Print: 2020-03-26

©2020 Walter de Gruyter GmbH, Berlin/Boston

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