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As time goes by, on that you can rely preservation of urine samples for morphological analysis of erythrocytes and casts

  • Jolien J. Luimstra , Rüya G. Koçer and Ayşe Y. Demir EMAIL logo

Corresponding author: Ayşe Y. Demir, MD, PhD, Laboratory for Clinical Chemistry and Hematology, Meander Medical Centre, Postbus 1502, 3800 BM Amersfoort, The Netherlands, Phone: +31-33-8504344, E-mail:

Funding source: Foundation Quality Funds for Medical Specialists (SKMS)

Award Identifier / Grant number: 55092985

Acknowledgments

We would like to thank the members of the Clinical Chemistry Society of the Netherlands (NVKC) workgroup Guideline ‘Unambiguous Laboratory Diagnostics in Hematuria’ for valuable discussions. We are also grateful to the laboratory staff of Meander Medical Centre, Mrs. Thea van der Valk-Rosendal in particular, for their practical support in obtaining and preparing samples.

  1. Research funding: This work was supported by the Foundation Quality Funds for Medical Specialists (SKMS, Project Number 55092985).

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

  4. Informed consent: Informed consent was obtained from all individuals included in this study.

  5. Ethical approval: Research involving human subjects complied with all relevant national regulations, institutional policies and is in accordance with the tenets of the Helsinki Declaration (as revised in 2013), and has been approved by the authors’ Institutional Review Board.

References

1. Martinez, MG, dos S Silva, V, do Valle, AP, Amaro, CR, Corrente, JE, Martin, LC. Comparison of different methods of erythrocyte dysmorphism analysis to determine the origin of hematuria. Nephron Clin Pract 2014;128:88–94. https://doi.org/10.1159/000367848.Search in Google Scholar PubMed

2. Rath, B, Turner, C, Hartley, B, Chantler, C. What makes red cells dysmorphic in glomerular haematuria? Pediatr Nephrol 1992;6:424–7. https://doi.org/10.1007/bf00874000.Search in Google Scholar PubMed

3. Komarova, O, van der Meer, W, Levtchenko, E, Monnens, L. Effective chemical preservation of morphology of urinary erythrocytes. Pediatr Nephrol 2003;18:665–6. https://doi.org/10.1007/s00467-003-1149-6.Search in Google Scholar PubMed

4. European Confederation of Laboratory Medicine. European urinalysis guidelines. Scand J Clin Lab Invest Suppl 2000;231:1–86.10.1080/00365513.2000.12056993Search in Google Scholar

5. CLSI. Urinalysis; approved guideline—third edition. CLSI document GP16-A3. Wayne, PA: Clinical and Laboratory Standards Institute; 2009.Search in Google Scholar

6. Kouri, T, Malminiemi, O, Penders, J, Pelkonen, V, Vuotari, L, Delanghe, J. Limits of preservation of samples for urine strip tests and particle counting. Clin Chem Lab Med 2008;46:703–13, https://doi.org/10.1515/cclm.2008.122.Search in Google Scholar PubMed

7. Huussen, J, Koene, RA, Hilbrands, LB. The (fixed) urinary sediment, a simple and useful diagnostic tool in patients with haematuria. Neth J Med 2004;62:4–9.Search in Google Scholar

8. Nagahama, D, Yoshiko, K, Watanabe, M, Morita, Y, Iwatani, Y, Matsuo, S. A useful new classification of dysmorphic urinary erythrocytes. Clin Exp Nephrol 2005;9:304–9. https://doi.org/10.1007/s10157-005-0380-9.Search in Google Scholar PubMed

9. Gelman, A, Hill, J. Data analysis using regression and multilevel/hierarchical models. Cambridge: Cambridge University Press; 2006.10.1017/CBO9780511790942Search in Google Scholar

10. Verbrugge, SE, Kemperman, H. Evaluation of the Stabilur urine vacuum tube for microscopic analysis of dysmorphic erythrocytes and erythrocyte casts. Ned Tijdschr Klin Chem Labgeneesk 2016;41:98.Search in Google Scholar

11. A comparative evaluation of spray coated urinalysis preservative tubes with current BD Vacutainer® Plus urinalysis preservative tubes for routine urinalysis testing on the Sysmex® UF-50 and Siemens Clinitek Atlas® Systems (white paper) Becton, Dickinson and Company. Becton, Dickinson and Company; 2009.Search in Google Scholar

Received: 2020-08-06
Accepted: 2020-11-05
Published Online: 2020-11-19
Published in Print: 2021-04-27

© 2020 Walter de Gruyter GmbH, Berlin/Boston

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