Skip to content
Licensed Unlicensed Requires Authentication Published by De Gruyter February 11, 2021

Paediatric reference intervals for ionised calcium – a data mining approach

Jason Zhi Yong Chung ORCID logo

Corresponding author: Jason Zhi Yong Chung, Department of Clinical Biochemistry, The Children’s Hospital at Westmead, Westmead, NSW2145, Australia; and The Children’s Hospital at Westmead Clinical School, The University of Sydney, Westmead, NSW2145, Australia, E-mail:

  1. Research funding: None declared.

  2. Author contributions: The author has accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: The author states no conflict of interest.

  4. Informed consent: Informed consent was not required for this study.

  5. Ethical approval: The local Institutional Review Board deemed the study exempt from review.

References

1. Lacher, DA, Hughes, JP, Carroll, MD. Estimate of biological variation of laboratory analytes based on the third national health and nutrition examination survey. Clin Chem 2005;51:450–2.10.1373/clinchem.2004.039354Search in Google Scholar PubMed

2. Tate, JR, Sikaris, KA, Jones, GRD, Yen, T, Koerbin, G, Ryan, J, et al.. Harmonising adult and paediatric reference intervals in Australia and New Zealand: an evidence-based approach for establishing a first panel of chemistry analytes. Clin Biochem Rev 2014;35:213–35.Search in Google Scholar

3. Bhattacharya, CG. A simple method of resolution of a distribution into Gaussian components. J Biometric Soc 1967;23:115–35.10.2307/2528285Search in Google Scholar

4. Jones, GRD, Haeckel, R, Loh, TP, Sikaris, K, Streichert, T, Katayev, A, et al.. Indirect methods for reference interval determination - review and recommendations. Clin Chem Lab Med 2018;57:20–9.10.1515/cclm-2018-0073Search in Google Scholar PubMed

5. Zierk, J, Arzideh, F, Kapsner, LA, Prokosch, H, Metzler, M, Rauh, M. Reference interval estimation from mixed distributions using truncation points and the Kolmogorov-smirnov distance (kosmic). Sci Rep 2020;10:1704.10.1038/s41598-020-58749-2Search in Google Scholar PubMed PubMed Central

6. Graham, J. Bhattacharya spread sheet excel application. Available from: http://www.sydpath.stvincents.com.au/ [Accessed Aug 2018].Search in Google Scholar

7. Nelson, N, Finnstrom, O, Larsson, L. Neonatal reference values for ionized calcium, phosphate and magnesium. Selection of reference population by optimality criteria. Scand J Clin Lab Invest 1987;47:111–7.10.3109/00365518709168878Search in Google Scholar

8. Wandrup, J, Kroner, J, Pryds, O, Kastrup, KW. Age-related reference values for ionized calcium in the first week of life in premature and full-term neonates. Scand J Clin Lab Invest 1988;48:255–60.10.3109/00365518809167492Search in Google Scholar PubMed

9. Marwaha, RK, Khadgawat, R, Tandon, N, Kanwar, R, Narang, A, Sastry, A, et al.. Reference intervals of serum calcium, ionized calcium, phosphate and alkaline phosphatase in healthy Indian school children and adolescents. Clin Biochem 2010;43:1216–9.10.1016/j.clinbiochem.2010.07.014Search in Google Scholar PubMed

10. Soldin, SJ, Wong, EC, Brugnara, C, Soldin, OP, editors. Paediatric reference intervals. Washingtom: AACC Press; 2017.Search in Google Scholar

11. Farrell, CJ, Nguyen, L, Carter, AC. Data mining for age-related TSH reference intervals in adulthood. Clin Chem Lab Med 2017;55:e213–5.10.1515/cclm-2016-1123Search in Google Scholar PubMed


Supplementary Material

The online version of this article offers supplementary material https://doi.org/10.1515/cclm-2021-0006.


Received: 2021-01-04
Accepted: 2021-01-25
Published Online: 2021-02-11
Published in Print: 2021-06-25

© 2021 Walter de Gruyter GmbH, Berlin/Boston

Scroll Up Arrow