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Licensed Unlicensed Requires Authentication Published by De Gruyter March 16, 2022

Diagnostic performance characteristics of the Quanta Flash Rheumatoid Factor assay in a consecutive Dutch patient cohort

  • Lotte Wieten , Jan G.M.C. Damoiseaux EMAIL logo , Bram Lestrade and Liesbeth E. Bakker-Jonges

Corresponding author: Jan G.M.C. Damoiseaux, PhD, Laboratory Specialist Medical Immunology, Central Diagnostic Laboratory, Maastricht University Medical Center, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands, Phone: +31 (0)43 3876655, E-mail:


The authors would like to thank Ad Heumassej and Tamara Cieremans for technical assistance and performing the assays.

  1. Research funding: None declared.

  2. Author contributions: All the authors meet the following four criteria: 1. Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; 2. Drafting the work or revising it critically for important intellectual content; 3. Final approval of the version to be published; and 4. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

  4. Informed consent: Informed consent was obtained from all individuals included in this study.

  5. Ethical approval: The research has complied with all relevant national regulations, institutional policies, and in accordance with the tenets of the Helsinki Declaration. Patient sera were obtained for routine clinical purposes and anonymously used for quality control purposes. According to the Dutch law, this does not require review by an Institutional Review Board.


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Supplementary Material

The online version of this article offers supplementary material (

Received: 2022-02-06
Accepted: 2022-03-04
Published Online: 2022-03-16
Published in Print: 2022-05-25

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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