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Licensed Unlicensed Requires Authentication Published by De Gruyter July 20, 2022

Complexity of serological assays and misunderstandings of WHO International Units

  • Ivana Knezevic ORCID logo EMAIL logo , Giada Mattiuzzo , Mark Page , Micha Nuebling , Elwyn Griffiths and Philip Minor

Corresponding author: Ivana Knezevic, MD, PhD, Department of Health Product Policy and Standards, World Health Organization, Avenue Appia 20, CH-1211 Geneva, Switzerland, Phone: +41 22 791 3136, E-mail:

  1. Research funding: None declared.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

  4. Informed consent: Not applicable.

  5. Ethical approval: Not applicable.


1. Hansen, YBL, Furuta, K, Devaraj, S, Yilmaz, FM, Nordin, G. Misleading nomenclature of units of WHO materials used for standardization of SARS CoV-2 serology. Clin Chem Lab Med 2022;60:e151–2. in Google Scholar PubMed

Received: 2022-07-11
Accepted: 2022-07-11
Published Online: 2022-07-20
Published in Print: 2022-09-27

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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