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BY-NC-ND 4.0 license Open Access Published by De Gruyter September 7, 2017

Optimization of diffusion imaging for multiple target regions using maximum likelihood estimation

  • Lars Bielak EMAIL logo and Michael Bock


In this work a procedure is proposed to determine an optimal distribution of b-values in diffusion MRI measu-rements. The optimization procedure uses a method of Maximum Likelihood Estimation which can operate on any given number of b-values, values of the diffusion coefficients (ADC) and measurement noise strengths. Optimal b-values are calculated for white and gray brain matter. An optimi-zation for more than one ADC is demonstrated using multiple target values.

Published Online: 2017-09-07

©2017 Lars Bielak et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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