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BY-NC-ND 4.0 license Open Access Published by De Gruyter September 22, 2018

Accelerated in vitro-calcification of potential urethane based heart valve replacement materials

  • Stefan Oschatz EMAIL logo , Stefanie Kohse , Volkmar Senz , Thomas Eickner , Klaus-Peter Schmitz and Niels Grabow

Abstract

Polycarbonate urethane and polyether urethane nonwovens as promising representatives of novel polymer heart valve materials were analysed regarding the susceptibility to calcification in comparison to porcine pericardium and polyamide 6. The applied method represents an accelerated calcification out of a metastable solution in short time with significant precipitates on the reference material. As our results show, urethane based nonwoven structures exhibit considerably lower susceptibility to calcification compared to pericardium as widely established material for leaflet design.

Published Online: 2018-09-22
Published in Print: 2018-09-01

© 2018 the author(s), published by Walter de Gruyter Berlin/Boston

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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