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BY 4.0 license Open Access Published by De Gruyter September 18, 2019

Numerical simulation and in vitro examination of the flow behaviour within coronary stents

  • Helena-Sophie Melzer EMAIL logo , Ralf Ahrens , Andreas E. Guber and Jakob Dohse

Abstract

This paper discusses the influence of different design parameters of stents by mathematical flow simulations and flow measurements using micro-particle image velocimetry (micro-PIV). A stent strut may cause recirculation areas, which are considered to be the source of thrombosis and the process of in-stent restenosis. The simulations showed that a reduced strut height and a chamfering of the struts reduce these recirculation zones. The numerically determined results were compared with experimental investigations. For this purpose metallic stent structures were transferred into transparent channel systems made of PDMS. The experimental investigations confirm the results of numerical simulations.

Published Online: 2019-09-18
Published in Print: 2019-09-01

© 2019 by Walter de Gruyter Berlin/Boston

This work is licensed under the Creative Commons Attribution 4.0 Public License.

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