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BY 4.0 license Open Access Published by De Gruyter September 18, 2019

Biocompatibility of magnetic iron oxide nanoparticles for biomedical applications

  • Claudia Matschegewski EMAIL logo , Anja Kowalski , Knut Müller , Henrik Teller , Niels Grabow , Swen Großmann , Klaus-Peter Schmitz and Stefan Siewert

Abstract

Magnetic nanoparticles are highly promising for the usage in various biomedical applications including magnetic particle imaging (MPI), cancer hyperthermia treatment or as drug carriers. The present study aims at assessing in vitro biocompatibility of two commercially available magnetic iron oxide nanoparticle formulations: dextran-based magnetic nanoparticle synomag-D and bionized nanoferrite BNF-starch. Biological performance of both nanoparticle formulations were studied in human endothelial cells by analyzing cell viability and nanoparticle internalization in order to judge their suitability as theranostics.

Published Online: 2019-09-18
Published in Print: 2019-09-01

© 2019 by Walter de Gruyter Berlin/Boston

This work is licensed under the Creative Commons Attribution 4.0 Public License.

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