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BY 4.0 license Open Access Published by De Gruyter November 26, 2020

A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography

  • Christoph Brandt-Wunderlich EMAIL logo , Franziska Bonin , Wolfram Schmidt , Niels Grabow , Klaus- Peter Schmitz , Swen Großmann , Michael Stiehm , Klaus-Peter Schmitz , Stefan Siewert and Alper Öner


Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of porcine coronary arteries via OCT is described. Diameter measurements based on OCT imaging were performed during consecutive pressurization of a porcine coronary artery from 40 to 200 mmHg in a physiological environment. The test results indicate that the radial compliance depends on the specific segment of the artery as well as the pressure range considered. The revealed compliance data can be used for numerical simulations of the vascular tissue as well as for optimization of in vitro test setups for pulsatile testing of vascular implants.

Published Online: 2020-11-26
Published in Print: 2020-09-01

© 2020 by Walter de Gruyter Berlin/Boston

This work is licensed under the Creative Commons Attribution 4.0 International License.

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