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BY 4.0 license Open Access Published by De Gruyter November 26, 2020

Permeability and wettability of bioresorbable nanofiber nonwoven membranes

  • Swen Großmann EMAIL logo , Jan Oldenburg , Robert Ott , Michael Stiehm , Klaus-Peter Schmitz , Stefan Siewert , Sabine Illner and Niels Grabow


Nanofiber nonwoven membranes produced by electrospinning provide the possibility to adjust mechanical material parameters as well as simultaneously the biologically relevant properties - a fundamental aspect in developing new implants and medical devices. Wettability and permeability are also of great importance, as they have a decisive influence on the release of drugs, cell attachment, degradability and finally the nutrient supply of the surrounding tissue. Within this work the wettability and permeability of several electrospun poly-L-lactide nonwovens, including different additives, were investigated and a correlation to membrane morphology was found. A potential modification of the permeability by the fluid viscosity was also investigated. The results form a fundamental building block in the development of permeable biodegradable implants and medical devices.

Published Online: 2020-11-26
Published in Print: 2020-09-01

© 2020 by Walter de Gruyter Berlin/Boston

This work is licensed under the Creative Commons Attribution 4.0 International License.

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