Skip to content
BY 4.0 license Open Access Published by De Gruyter November 26, 2020

Permeability and wettability of bioresorbable nanofiber nonwoven membranes

Swen Großmann EMAIL logo , Jan Oldenburg , Robert Ott , Michael Stiehm , Klaus-Peter Schmitz , Stefan Siewert , Sabine Illner and Niels Grabow

Abstract

Nanofiber nonwoven membranes produced by electrospinning provide the possibility to adjust mechanical material parameters as well as simultaneously the biologically relevant properties - a fundamental aspect in developing new implants and medical devices. Wettability and permeability are also of great importance, as they have a decisive influence on the release of drugs, cell attachment, degradability and finally the nutrient supply of the surrounding tissue. Within this work the wettability and permeability of several electrospun poly-L-lactide nonwovens, including different additives, were investigated and a correlation to membrane morphology was found. A potential modification of the permeability by the fluid viscosity was also investigated. The results form a fundamental building block in the development of permeable biodegradable implants and medical devices.

Published Online: 2020-11-26
Published in Print: 2020-09-01

© 2020 by Walter de Gruyter Berlin/Boston

This work is licensed under the Creative Commons Attribution 4.0 International License.

Downloaded on 1.2.2023 from https://www.degruyter.com/document/doi/10.1515/cdbme-2020-3119/html
Scroll Up Arrow