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BY 4.0 license Open Access Published by De Gruyter October 9, 2021

Fluid dynamics in the human heart: Altered vortex formation and wash-out in mitral regurgitation simulations

  • Jochen Brenneisen , Carlo Wentzel , Farokh Karwan , Olaf Dössel and Axel Loewe


Mitral regurgitation alters the flow conditions in the left ventricle. To account for quantitative changes and to investigate the behavior of different flow components, a realistic computational model of the whole human heart was employed in this study. While performing fluid dynamics simulations, a scalar transport equation was solved to analyze vortex formation and ventricular wash-out for different regurgitation severities. Additionally, a particle tracking algorithm was implemented to visualize single components of the blood flow. We confirmed a significantly lowered volume of the direct flow component as well as a higher vorticity in the diseased case.

Published Online: 2021-10-09
Published in Print: 2021-10-01

© 2021 The Author(s), published by Walter de Gruyter GmbH, Berlin/Boston

This work is licensed under the Creative Commons Attribution 4.0 International License.

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