Ján Labuda, et al.
Pure and Applied Chemistry, 2018 published online ahead of print 29 May 2018
Bioanalytical chemistry is a branch of science that represents large and dynamic areas of research and practical analytical activities, from human health screening (medical, clinical, food, and pharmaceutical analysis) to forensic analysis and from basic biochemistry studies to special apparatus development. Bioanalytical chemistry and biochemical analysis often require special methods for sampling and sample preparation and for handling biomolecules, including isolation, purification, separation, and fragmentation. Special attention is paid to apparatus and to techniques with immobilised bioreceptors (biosensors, bioarrays). The methods of analysis and identification of biomacromolecules are radically different from those used to analyse relatively small organic molecules. Most “classical” analytical methods are not suitable for the analysis of biomacromolecules or are suitable only to a limited extent.
Recommendations are given concerning the terminology of methods of bioanalytical chemistry. With respect to dynamic development particularly in the analysis and investigation of biomacromolecules, terms related to bioanalytical samples, enzymatic methods, immunoanalytical methods, methods used in genomics and nucleic acid analysis, proteomics, metabolomics, glycomics, lipidomics, and biomolecules interaction studies are introduced.
These recommendations will become part of a chapter in the revised Orange Book (Compendium of Terminology in Analytical Chemistry, 4th edition).
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