Forward Osmosis (FO)-Nanofiltration (NF) integration as the final product polishing step enables high concentration of acetic acid output through continuous dehydration of fermentation derived product. A mathematical transport model has been developed based on external and internal concentration polarization modulus of FO and extended Nernst–Plank equation for NF to capture the flux and rejection trends from those membranes. The modular designed production scheme ensured high flux (45 Lm−2 h−1), concentration (962 g L−1) and purity (>98 %) of acetic acid under non-neutralization condition. Excellent performance of the model is reflected in low relative error (<0.05), high Willmott d-index (>0.97) and high correlation coefficient (>0.98).
Funding source: Department of Science and Technology
Award Identifier / Grant number: DST-FIST
Funding statement: Department of Science and Technology, Ministry of Science and Technology, Funder Id: http://dx.doi.org/10.13039/501100001409, Grant Number: DST-FIST
The authors acknowledge financial support under DST-FIST Program and Ministry of Human Resource Development of the Government of India.
 Nayak J, Pal P. Transforming waste cheese–whey into acetic acid through a continuous membrane-integrated hybrid process. Ind Eng Chem Res. 2013;52:2977–84.10.1021/ie3033729Search in Google Scholar
 Law JY, Mohammad AW, Tee ZK, Zaman NK, Jahim J, Santanaraj J, et al. Recovery of succinic acid from fermentation broth by forward osmosis-assisted crystallization process. J Membr Sci. 2019;583:139–51.10.1016/j.memsci.2019.04.036Search in Google Scholar
 Nayak J, Pal M, Pal P. Modeling and simulation of direct production of acetic acid from cheese whey in a multi-stage membrane-integrated bioreactor. Biochem Eng J. 2015;93:179–95.10.1016/j.bej.2014.10.002Search in Google Scholar
 Pal P, Nayak J. Development and analysis of a sustainable technology in manufacturing acetic acid and whey protein from waste cheese whey. J Cleaner Prod. 2016;112:59–70.10.1016/j.jclepro.2015.07.085Search in Google Scholar
 Phuntsho S, Sahebi S, Majeed T, Lotfi F, Kim JE, Shon HK. Assessing the major factors affecting the performances of forward osmosis and its implications on the desalination process. Chem Eng J. 2013;231:484–96.10.1016/j.cej.2013.07.058Search in Google Scholar
 Senta I, Mato M, Jakopovic HK, Terzica S, Urkob J, Mijatovi I, et al. Removal of antimicrobials using advanced wastewater treatment. J Hazard Mater. 2011;192:319–28.10.1016/j.jhazmat.2011.05.021Search in Google Scholar
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