Corrigendum to: Clinical benefit of measuring both haemoglobin and transferrin concentrations in faeces: demonstration during a large-scale colorectal cancer screening trial in Japan

Corrigendum to: Yoshinori Takashima, Takao Shimada and Tamotsu Yokozawa. January 2015. Clinical benefit of measuring both haemoglobin and transferrin concentrations in faeces: demonstration during a large-scale colorectal cancer screening trial in Japan. Diagnosis. Volume 2, Issue 1, pages 53–59. (DOI 10.1515/dx-2014-0052):

On page 53, the last keyword should correctly read transferrin. On page 55 it is stated that 10 μg Hb/g faeces for Tf, however, it should correctly read that 10 μg Tf/g faeces for Tf. Thus, the last sentence of the first paragraph on page 55 should correctly read: In the present study, the cut-off concentrations were set at 20 μg Hb/g faeces for Hb and 10 μg Tf/g faeces for Tf, which are the standard cut-off concentrations that are used most widely in Japan [5].

Furthermore, it is stated on page 56 (left column): Figure 1A shows the concentrations of Hb and Tf on the logarithmic x- and y-axes, respectively, and their cut-off concentrations. The vertical line is the cut-off concentration for Hb and the horizontal line is the cut-off concentration for Tf. Unfortunately, the horizontal line is missing in Figure 1A. The y-axes of all panels of Figure 1 are incorrectly labelled. It should correctly read: TF concentration, μg Tf/ faeces. In Figure 1B, the labelling on the function lines is incomplete. It should read Hb/Tf=100/1 and Hb/Tf=50/1, respectively. The correct Figure 1 is shown below.

Figure 1:

Relationship between haemoglobin (Hb) and transferrin (Tf).

(A) Areas divided based on the Hb and Tf cut-off concentrations. The data are plotted on logarithmic axes. (B) Hb-intact and Hb-denatured areas. (C) Constipated group. (D) Non-constipated group. (B)–(D) The data ranges on the x- and y-axes have been reduced by 50 times relative to that used in (A) to illustrate the trends more clearly.