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BY-NC-ND 4.0 license Open Access Published by De Gruyter Open Access June 28, 2018

Fabrication of radially aligned electrospun nanofibers in a three-dimensional conical shape

Michel Vong and Norbert Radacsi EMAIL logo
From the journal Electrospinning

Abstract

This paper reports on the rapid fabrication of radially-aligned, three-dimensional conical structures by electrospinning. Three different polymers, Polyvinylpyrrolidone, Polystyrene and Polyacrylonitrile were used to electrospin the cones. These cone structures are spreading out from a vertical conductive pillar, which can be arbitrarily placed on specific part of the collector. The lower part of the cone is clearly defined on the collector, and the cone has a relatively uniform radius around the pillar. The cones are constituted of fibers that are radially aligned towards the top of the pillar, but there is no apex and the fibers fall flat on the top of the pillar surface. A parametric study has been performed to investigate the effects of the pillar morphology (height and thickness) and the electrospinning parameters (applied voltage and working distance) on the overall shape and size of the cone structure, as well as the fiber alignment. The pillar morphology influences directly the cone diameter and height. The electrospinning parameters have little effect on the cone structure. The formation mechanism has been identified to be related to the shape of the electric field, which has been systematically simulated to understand the effect of the electric field lines on the final dimensions of the cone structure.

References

[1] Xue J, Xie J, LiuW, Xia Y, Electrospun Nanofibers: New Concepts, Materials, and Applications, Acc Chem Res. 50, 2017, 1976.Search in Google Scholar

[2] Thenmozhi S, Dharmaraj N, Kadirvelu K, Kim HY, Electrospun nanofibers: New generation materials for advanced applications, Mater Sci Eng B. 217, 2017, 36.10.1016/j.mseb.2017.01.001Search in Google Scholar

[3] Jian S, Zhu J, Jiang S, Chen S, Fang H, Song Y, et al., Nanofibers with diameter below one nanometer from electrospinning, RSC Adv. 8, 2018, 4794.Search in Google Scholar

[4] Katsogiannis KAG, VladisavljevićGT, Georgiadou S, Porous electrospun polycaprolactone (PCL) fibres by phase separation, Eur Polym J. 69, 2015, 284.10.1016/j.eurpolymj.2015.01.028Search in Google Scholar

[5] Huang Z-X, Wu J-W, Wong S-C, Qu J-P, Srivatsan TS, The technique of electrospinning for manufacturing core-shell nanofibers, Mater Manuf Process. 33, 2018, 202.10.1080/10426914.2017.1303144Search in Google Scholar

[6] Feltz KP, Kalaf EAG, Chen C, Martin RS, Sell SA, A review of electrospinning manipulation techniques to direct fiber deposition and maximize pore size, Electrospinning. 1, 2017, 46.10.1515/esp-2017-0002Search in Google Scholar

[7] Al-Ajrah S, Lafdi K, Liu Y, Le Coustumer P, Fabrication of ceramic nanofibers using polydimethylsiloxane and polyacrylonitrile polymer blends, J Appl Polym Sci. 135, 2018, 45967.10.1002/app.45967Search in Google Scholar

[8] Chen C, Tang Y, Vlahovic B, Yan F, Electrospun Polymer Nanofibers Decoratedwith Noble Metal Nanoparticles for Chemical Sensing, Nanoscale Res Lett. 12, 2017, 451.10.1186/s11671-017-2216-4Search in Google Scholar PubMed PubMed Central

[9] Zhang C,Wang X, Zhang E, Yang L, Yuan H, TuW, et al., An epigenetic bioactive composite scaffold with well-aligned nanofibers for functional tendon tissue engineering, Acta Biomater. 66, 2018, 141.10.1016/j.actbio.2017.09.036Search in Google Scholar PubMed

[10] Pedersbaek D, Frantzen MT, Fojan P, Electrospinning of Core-Shell Fibers for Drug Release Systems, J Self-Assembly Mol Electron. 5, 2017, 17.10.13052/jsame2245-4551.5.002Search in Google Scholar

[11] Alavarse AC, de Oliveira Silva FW, Colque JT, da Silva VM, Prieto T, Venancio EC, et al., Tetracycline hydrochloride-loaded electrospun nanofibers mats based on PVA and chitosan for wound dressing, Mater Sci Eng C. 77, 2017, 271.10.1016/j.msec.2017.03.199Search in Google Scholar PubMed

[12] Chou S-F, Woodrow KA, Relationships between mechanical properties and drug release from electrospun fibers of PCL and PLGA blends, J Mech Behav Biomed Mater. 65, 2017, 724.10.1016/j.jmbbm.2016.09.004Search in Google Scholar PubMed PubMed Central

[13] Jing L, Shim K, Toe CY, Fang T, Zhao C, Amal R, et al., Electrospun Polyacrylonitrile-Ionic Liquid Nanofibers for Superior PM 2.5 Capture Capacity, ACS ApplMater Interfaces. 8, 2016, 7030.Search in Google Scholar

[14] Yousef A, Brooks RM, El-Halwany MM, Abutaleb A, El-Newehy MH, Al-Deyab SS, et al., Electrospun CoCr 7 C 3 -supported C nanofibers: Effective, durable, and chemically stable catalyst for H 2 gas generation from ammonia borane, Mol Catal. 434, 2017, 32.10.1016/j.mcat.2017.02.036Search in Google Scholar

[15] Yang X, Li X, Zhang L, Gong J, Electrospun template directed molecularly imprinted nanofibers incorporated with BiOI nanoflake arrays as photoactive electrode for photoelectrochemical detection of triphenyl phosphate, Biosens Bioelectron. 92, 2017, 61.10.1016/j.bios.2017.01.056Search in Google Scholar PubMed

[16] Mercante LA, Pavinatto A, Iwaki LEO, Scagion VP, Zucolotto V, Oliveira ON, et al., Electrospun Polyamide 6/Poly(allylamine hydrochloride) Nanofibers Functionalized with Carbon Nanotubes for Electrochemical Detection of Dopamine, ACS Appl Mater Interfaces. 7, 2015, 4784.Search in Google Scholar

[17] Jindal A, Narayanan H, Basu S, Direct Formic Acid PEM Fuel Cell with Electrospun Carbon Nitride Nanofibers as Cathode Catalyst, Fuel Cells. 17, 2017, 407.10.1002/fuce.201600209Search in Google Scholar

[18] Hong S, Hou M, Zhang H, Jiang Y, Shao Z, Yi B, A highperformance PEM fuel cell with ultralow platinum electrode via electrospinning and underpotential deposition, Electrochim Acta. 245, 2017, 403.10.1016/j.electacta.2017.05.066Search in Google Scholar

[19] Yu L, Shao Z, Xu L, Wang M, High Throughput Preparation of Aligned Nanofibers Using an Improved Bubble-Electrospinning, Polymers (Basel). 9, 2017, 658.10.3390/polym9120658Search in Google Scholar PubMed PubMed Central

[20] Hwang W, Pang C, Chae H, Fabrication of aligned nanofibers by electric-field-controlled electrospinning: insulating-block method, Nanotechnology. 27, 2016, 435301.10.1088/0957-4484/27/43/435301Search in Google Scholar PubMed

[21] Xie J, MacEwan MR, Liu W, Jesuraj N, Li X, Hunter D, et al., Nerve Guidance Conduits Based on Double-Layered Scaffolds of Electrospun Nanofibers for Repairing the Peripheral Nervous System, ACS Appl Mater Interfaces. 6, 2014, 9472.10.1021/am5018557Search in Google Scholar PubMed PubMed Central

[22] Tamura T, Kawakami H, Aligned Electrospun Nanofiber Composite Membranes for Fuel Cell Electrolytes, Nano Lett. 10, 2010, 1324.Search in Google Scholar

[23] Zhu J, Chen L, Xu Z, Lu B, Electrospinning preparation of ultralong aligned nanofibers thin films for high performance fully flexible lithium-ion batteries, Nano Energy. 12, 2015, 339.10.1016/j.nanoen.2014.10.026Search in Google Scholar

[24] Sadrjahani M, Gharehaghaji AA, Javanbakht M, Aligned electrospun sulfonated polyetheretherketone nanofiber based proton exchange membranes for fuel cell applications, Polym Eng Sci. 57, 2017, 789.10.1002/pen.24453Search in Google Scholar

[25] Pauly HM, Kelly DJ, Popat KC, Trujillo NA, Dunne NJ, McCarthy HO, et al., Mechanical properties and cellular response of novel electrospun nanofibers for ligament tissue engineering: Effects of orientation and geometry, J Mech Behav Biomed Mater. 61, 2016, 258.10.1016/j.jmbbm.2016.03.022Search in Google Scholar PubMed

[26] Fee T, Downs C, Eberhardt A, Zhou Y, Berry J, Image-based quantification of fiber alignmentwithin electrospun tissue engineering scaffolds is related to mechanical anisotropy, J Biomed Mater Res Part A. 104, 2016, 1680.Search in Google Scholar

[27] Mellor LF, Huebner P, Cai S, Mohiti-Asli M, Taylor MA, Spang J, et al., Fabrication and Evaluation of Electrospun, 3D-Bioplotted, and Combination of Electrospun/3D-Bioplotted Scaffolds for Tissue Engineering Applications, Biomed Res Int. 2017, 2017, 1.Search in Google Scholar

[28] Shen C, Wycisk R, Pintauro PN, High performance electrospun bipolar membrane with a 3D junction, Energy Environ Sci. 10, 2017, 1435.Search in Google Scholar

[29] Matulevicius J, Kliucininkas L, Martuzevicius D, Krugly E, Tichonovas M, Baltrusaitis J, Design and Characterization of Electrospun Polyamide Nanofiber Media for Air Filtration Applications, J Nanomater. 2014, 2014, 1.Search in Google Scholar

[30] Zhang Q, Welch J, Park H, Wu C-Y, Sigmund W, Marijnissen JCM, Improvement in nanofiber filtration by multiple thin layers of nanofiber mats, J Aerosol Sci. 41, 2010, 230.10.1016/j.jaerosci.2009.10.001Search in Google Scholar

[31] Soliman S, Pagliari S, Rinaldi A, Forte G, Fiaccavento R, Pagliari F, et al., Multiscale three-dimensional scaffolds for soft tissue engineering via multimodal electrospinning, Acta Biomater. 6, 2010, 1227.Search in Google Scholar

[32] Tzezana R, Zussman E, Levenberg S, A Layered Ultra-Porous Scaffold for Tissue Engineering, Created via a Hydrospinning Method, Tissue Eng Part C Methods. 14, 2008, 281.10.1089/ten.tec.2008.0201Search in Google Scholar PubMed

[33] Pham QP, Sharma U, Mikos AG, Electrospun Poly(ε- caprolactone) Microfiber and Multilayer Nanofiber/Microfiber Scaffolds: Characterization of Scaffolds and Measurement of Cellular Infiltration, Biomacromolecules. 7, 2006, 2796.10.1021/bm060680jSearch in Google Scholar PubMed

[34] Cai Y-Z, Zhang G-R, Wang L-L, Jiang Y-Z, Ouyang H-W, Zou X-H, Novel biodegradable three-dimensional macroporous scaffold using aligned electrospun nanofibrous yarns for bone tissue engineering, J Biomed Mater Res Part A. 100A, 2012, 1187.10.1002/jbm.a.34063Search in Google Scholar PubMed

[35] KimMS, Son J, Lee H,Hwang H, Choi CH, Kim G, Highly porous 3D nanofibrous scaffolds processed with an electrospinning/laser process, Curr Appl Phys. 14, 2014, 1.10.1016/j.cap.2013.10.008Search in Google Scholar

[36] Moazeni N, Semnani D, Rafeinia M, Hasani H, Naeimi M, Sadrjahani M, The effect of electrospinning parameters on the compliance behavior of electrospun polyurethane tube for artificial common bile duct, Polym Sci Ser A. 59, 2017, 67.10.1134/S0965545X17010114Search in Google Scholar

[37] Mi H-Y, Jing X, Napiwocki BN, Li Z-T, Turng L-S, Huang H-X, Fabrication of fibrous silica sponges by self-assembly electrospinning and their application in tissue engineering for threedimensional tissue regeneration, Chem Eng J. 331, 2018, 652.10.1016/j.cej.2017.09.020Search in Google Scholar

[38] Sun B, Long YZ, Zhang HD, Li MM, Duvail JL, Jiang XY, et al., Advances in three-dimensional nanofibrous macrostructures via electrospinning, Prog Polym Sci. 39, 2014, 862.10.1016/j.progpolymsci.2013.06.002Search in Google Scholar

[39] Daming Z, Jiang C, Electrospinning of three-dimensional nanofibrous tubes with controllable architectures, Nano Lett. 8, 2008, 3283.Search in Google Scholar

[40] Ostrowska B, Jaroszewicz J, Zaczynska E, Tomaszewski W, Swieszkowski W, Kurzydlowski KJ, Evaluation of 3D hybrid microfiber/nanofiber scaffolds for bone tissue engineering, Bull Polish Acad Sci Tech Sci. 62, 2014, 551.10.2478/bpasts-2014-0059Search in Google Scholar

[41] Domalik-Pyzik P, Morawska-Chochół A, Chłopek J, Rajzer I, Wrona A, Menaszek E, et al., Polylactide/polycaprolactone asymmetric membranes for guided bone regeneration, EPolymers. 16, 2016, 351.10.1515/epoly-2016-0138Search in Google Scholar

[42] Lowe CJ, Reucroft IM, Grota MC, Shreiber DI, Production of Highly Aligned Collagen Scaffolds by Freeze-drying of Selfassembled, Fibrillar Collagen Gels, ACS Biomater Sci Eng. 2, 2016, 643.10.1021/acsbiomaterials.6b00036Search in Google Scholar PubMed PubMed Central

[43] McMurtrey RJ, Patterned and functionalized nanofiber scaffolds in three-dimensional hydrogel constructs enhance neurite outgrowth and directional control, J Neural Eng. 11, 2014, 66009.10.1088/1741-2560/11/6/066009Search in Google Scholar PubMed

[44] Vong M, Speirs E, Klomkliang C, Akinwumi I, Nuansing W, Radacsi N, Controlled three-dimensional polystyrene microand nano-structures fabricated by three-dimensional electrospinning, RSC Adv. 8, 2018, 15501.10.1039/C7RA13278FSearch in Google Scholar

[45] Xie J, MacEwan MR, Ray WZ, Liu W, Siewe DY, Xia Y, Radially Aligned, Electrospun Nanofibers as Dural Substitutes forWound Closure and Tissue Regeneration Applications, ACS Nano. 4, 2010, 5027.10.1021/nn101554uSearch in Google Scholar PubMed PubMed Central

[46] Li X, Li M, Sun J, Zhuang Y, Shi J, Guan D, et al., Radially Aligned Electrospun Fibers with Continuous Gradient of SDF1 for the Guidance of Neural Stem Cells, Small. 12, 2016, 5009.Search in Google Scholar

[47] Zhu Y, Cao Y, Pan J, Liu Y, Macro-alignment of electrospun fibers for vascular tissue engineering, J Biomed Mater Res Part B Appl Biomater. 92B, 2009, 508.10.1002/jbm.b.31544Search in Google Scholar PubMed

[48] Theron A, Zussman E, Yarin AL, Electrostatic field-assisted alignment of electrospun nanofibres, Nanotechnology. 12, 2001, 384.10.1088/0957-4484/12/3/329Search in Google Scholar

[49] Zhou W, Li Z, Zhang Q, Liu Y, Wei F, Luo G, Gas Flow-Assisted Alignment of Super Long Electrospun Nanofibers, J Nanosci Nanotechnol. 7, 2007, 2667.Search in Google Scholar

[50] Yang H, Kim S, Huh I, Kim S, Lahiji SF, Kim M, et al., Rapid implantation of dissolving microneedles on an electrospun pillar array, Biomaterials. 64, 2015, 70.10.1016/j.biomaterials.2015.06.027Search in Google Scholar PubMed

[51] Pan C, Han Y, Dong L, Wang J, Gu Z, Electrospinning of Continuous, Large Area, Latticework Fiber onto Two-Dimensional Pinarray Collectors, J Macromol Sci Part B. 47, 2008, 735.10.1080/00222340802118382Search in Google Scholar

[52] Zheng G, Li W, Wang X, Wu D, Sun D, Lin L, Precision deposition of a nanofibre by near-field electrospinning, J Phys D Appl Phys. 43, 2010, 415501.10.1088/0022-3727/43/41/415501Search in Google Scholar

[53] Sharma CS, Katepalli H, Sharma A, Madou M, Fabrication and electrical conductivity of suspended carbon nanofiber arrays, Carbon N Y. 49, 2011, 1727.Search in Google Scholar

[54] Chang T-L, Huang C-H, Chou S-Y, Tseng S-F, Lee Y-W, Direct fabrication of nanofiber scaffolds in pillar-based microfluidic device by using electrospinning and picosecond laser pulses, Microelectron Eng. 177, 2017, 52.10.1016/j.mee.2017.01.036Search in Google Scholar

[55] RAWAT A, MAHAVAR HK, TANWAR A, SINGH PJ, Study of electrical properties of polyvinylpyrrolidone/polyacrylamide blend thin films, Bull Mater Sci. 37, 2014, 273.10.1007/s12034-014-0639-4Search in Google Scholar

[56] Qi X-Y, Yan D, Jiang Z, Cao Y-K, Yu Z-Z, Yavari F, et al., Enhanced Electrical Conductivity in Polystyrene Nanocomposites at Ultra-Low Graphene Content, ACS Appl Mater Interfaces. 3, 2011, 3130.Search in Google Scholar

[57] Ahmad A, Isa KBM, Osman Z, Conductivity and structural studies of plasticized polyacrylonitrile (PAN)-lithiumtriflate polymer electrolyte films, Sains Malaysiana. 40, 2011, 691.Search in Google Scholar

[58] Collins G, Federici J, Imura Y, Catalani LH, Charge generation, charge transport, and residual charge in the electrospinning of polymers: A review of issues and complications, J Appl Phys. 111, 2012, 44701.10.1063/1.3682464Search in Google Scholar

Received: 2018-03-08
Accepted: 2018-05-09
Published Online: 2018-06-28

© 2018 Norbert Radacsi, published by De Gruyter

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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