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Licensed Unlicensed Requires Authentication Published by De Gruyter March 28, 2017

Protective effects of proanthocyanidins extracts from the bark of deciduous trees in lipid systems

  • Sarmite Janceva EMAIL logo , Liga Lauberte , Tatiana Dizhbite , Jelena Krasilnikova , Galina Telysheva and Marcis Dzenis
From the journal Holzforschung

Abstract

Oligomeric proanthocyanidins (OPC) rich extracts (OPCEs) were isolated by sequential extraction from the bark of the deciduous trees grey alder (Alnus incana), black alder (Alnus glutinosa) and goat willow (Salix caprea). The yields of OPCE from all barks under study were rather similar and varied between 12.3% and 15.4% based on the oven dry (o.d.) bark. Content of proanthocyanidins in OPCEs ranged from 16.6% to 25% based on o.d. extract. The OPCEs were characterised by means of antioxidant activity with ABTS˙+ and DPPH˙ radical scavenging tests. All extracts being introduced into lipid-based substrates, i.e. mayonnaise and a basic composition of a cosmetic cream, showed antioxidant activity comparable to the reference commercial antioxidant tert-butylhydroquinone (TBHQ). The results of in vitro tests have revealed that the OPCEs could be useful for the human organism as they activated malfunctions of amylase, inhibited pancreatic lipase activity (duodenal digestion model), decreased lipid absorption in blood and decreased pyruvate level in blood plasma essential for regulation of carbohydrate metabolism. The data obtained confirms the advantages of OPC and OPCEs applications as an antioxidant additive for food, cosmetic and health industries.

Acknowledgements

The authors gratefully acknowledge the financial support from the Latvian budget, National Research Programme “Forest and earth entrails resources: research and sustainable utilisation – new products and technologies” (ResProd) Project Nr. 3 “Biomaterials and products from forest resources with versatile applicability” and grant 564/2012.

References

Baltrušaitytė, V., Venskutonis, P.R., Čeksterytė, V. (2007) Radical scavenging activity of different floral origin honey and beebread phenolic extracts. Food Chem. 101:502–514.10.1016/j.foodchem.2006.02.007Search in Google Scholar

Blainski, A., Lopes, G.C., Palazzo de Mello, J.C. (2013) Application and analysis of the Folin Ciocalteu method for determination of the total phenolic content from Limonium brasilience. Molecule 18:6852–6865.10.3390/molecules18066852Search in Google Scholar PubMed PubMed Central

Chun-Yang, L., Shi-Ying, X., Zhang, W. (2004) Vanillin-HCl assay for the proanthocyanidins content of grape seed and stem. Food Sci. 25:157–161.Search in Google Scholar

Dizhbite, T., Telysheva, G., Jurkjane, V., Viesturs, U. (2004) Characterizations of the radical scavenging activity of lignin – natural antioxidants. Bioresour Technol. 95:309–317.10.1016/j.biortech.2004.02.024Search in Google Scholar PubMed

González-Laredo R.F., Helm, R.F., Chen, J., Karchesy, J.J. (1998) Two acylated diarylheptanoid glycosides from red alder bark. J Nat Prod. 61:1292–1294.10.1021/np980083lSearch in Google Scholar PubMed

González-Laredo R.F., Chen, J., Karchesy Y.M., Karchesy, J.J. (1999) Four new diarylheptanoid glycosides from Alnus rubra bark. Nat Prod Lett. 13:75–80.10.1080/10575639908048826Search in Google Scholar

Janceva, S., Dizhbite, T., Vevere, L., Telysheva, G., Dzenis, M. (2016a) Characterization of bark rich-in-tannins extracts from deciduous trees with emphasis on their antioxidant activity. IOP Conference Series: Materials Science and Engineering 111, Baltic Polymer Symposium 2015:1–4.10.1088/1757-899X/111/1/012013Search in Google Scholar

Janceva, S., Dizhbite, T., Telysheva, G., Vevere, L., Krasilnikova, J., Dzenis, M. (2016b) Assessment of alder trees bark potential as a renewable source of proanthocyanidins in Latvia. Mat Sci Appl. 33:26–30.10.1515/msac-2016-0005Search in Google Scholar

Krasilnikova, J., Telysheva, G., Dizhbite, T., Janceva, S., Andersone, A., Lauberts, M. (2013) Activity of bark of European deciduous trees and their condensed tannins (proantocianidins) towards amylase in saliva. Proceedings of the 2nd International Conference on Food Digestion (COST Action FA1005 INFOGEST): pp. 170.Search in Google Scholar

Liimatainen, J., Karonen, M., Sinkkonen, J., Helander, M., Salminen, J.D. (2012). Characterization of phenolic compounds from inner bark of Betula pendula. Holzforschung 66:171–181.10.1515/HF.2011.146Search in Google Scholar

Novaković, M., Stanković, M., Vučković, I., Todorović, N., Trifunović, S., Tešević, V., Vajs, V., Milosavljević, S. (2013) Diarylheptanoids from Alnus glutinosa bark and their chemoprotective effect on human lymphocytes DNA. Planta Med. 79:499–505.10.1055/s-0032-1328301Search in Google Scholar PubMed

Park, D., Kim, H.J., Jung, S.Y., Yook, C.S., Jin, C., Lee, Y.S. (2010) A new diarylheptanoid glycoside from the stem bark of Alnus hirsuta and protective effects of diarylheptanoid derivatives in human HepG2 cells. Chem Pharm Bull (Tokyo) 58: 238–241.10.1248/cpb.58.238Search in Google Scholar PubMed

Raal, A., Boikova, T., Püssa, T. (2015) Content and dynamics of polyphenols in Betula spp. leaves naturally growing in Estonia. Rec Nat Prod. 9:41–48.Search in Google Scholar

Riethmüller, E., Alberti, A., Tóth, G., Béni, S., Ortolano, F., Kéry, A. (2013) Characterisation of diarylheptanoid- and flavonoid-type phenolics in Corylus avellana L. leaves and bark by HPLC/DAD-ESI/MS. Phytochem Anal. 24:493–503.10.1002/pca.2452Search in Google Scholar

Schofield, P., Mbugua, D.M., Pell, A.N. (2001) Analysis of condensed tannins: a review. Anim Feed Sci Techn. 91:21–40.10.1016/S0377-8401(01)00228-0Search in Google Scholar

Suga, T., Ohta, S., Hirata, T., Aoki T. (1982) The absolute confuguration of diarylheptanoid xyloside, oregonin, isolated from the female flowers of Alnus serrulatoides. Chem Lett. 11:895–898.10.1246/cl.1982.895Search in Google Scholar

Telysheva, G., Dizhbite, T., Bikovens, O., Ponomarenko, J., Janceva, S., Krasilnikova, J. (2011) Structure and antioxidant activity of diarylheptanoids extracted from bark of grey alder (Alnus incana) and potential of biorefinery-based bark processing of European trees. Holzforschung 65:623–629.10.1515/hf.2011.096Search in Google Scholar

Tejero, I., Gonzáles-Garcia, N., Gonzalez-Lafont, A., Lluch, J.M. (2007) Tunneling in green tea: understanding the antioxidant activity of catechol-containing compounds. A variational transition – state theory study. J Am Chem Soc. 129:5846–5854.10.1021/ja063766tSearch in Google Scholar

Thompson, D., Moldéus, P. (1988) Cytotoxicity of butylated hydroxyanisole and butylated hydroxytoluene in isolated rat hepatocytes. Biochem Pharmacol. 37:2201–2207.10.1016/0006-2952(88)90582-5Search in Google Scholar

Trojakova, L., Reblova, Z., Pokorny, J. (1999) Determination of the oxidative stability of fats and oils using the Oxipres apparatus. Czech J Food Sci. 17:68–72.Search in Google Scholar

Received: 2016-10-14
Accepted: 2017-2-20
Published Online: 2017-3-28
Published in Print: 2017-7-26

©2017 Walter de Gruyter GmbH, Berlin/Boston

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