Abstract
Platelets have attracted substantial attention in the current decade owing to their unexpected pleiotropic properties and conflicted functions. In fact, platelets participate in both health (hemostasis) and disease (thrombotic diseases). Much of the plasticity of platelets comes from the fact that platelets are the reservoir and the ‘natural factory’ of growth factors (GFs), with pivotal functions in wound repair and tissue regeneration. By combining the platelets’ plasticity and biotechnological processes, PlateInnove Biotechnology optimized the production of GFs in nanoparticle biointerfacing by platelet content, which opens an avenue of possibilities.
Funding source: São Paulo Research Foundation
Award Identifier / Grant number: 2016/14459-3
Award Identifier / Grant number: 2017/26317-1
Funding statement: The authors would like to thank the support of Hemocentro de Campinas/UNICAMP, Colsan (Associação Beneficente de Coleta de Sangue), Hemocentro de Ribeirão Preto/USP, and the São Paulo Research Foundation (FAPESP) under grant 2016/14459-3 and 2017/26317-1.
Conflict of interest statement: Sheila Siqueira Andrade is the founder and Executive Director of PlateInnove Biotechnology, São Paulo, Brazil.
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Supplementary Material
The online version of this article offers supplementary material (https://doi.org/10.1515/hsz-2019-0342).
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