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Publicly Available Published by De Gruyter January 14, 2013

Transsphenoidal endoscopic skull base surgery: state of the art and future perspective

  • Aaron R. Cutler , Garni Barkhoudarian , Chester F. Griffiths and Daniel F. Kelly EMAIL logo
From the journal Innovative Neurosurgery


Given refinements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques and anatomical understanding, the endonasal endoscopic approach is now a well-accepted and widely utilized technique for removal of many if not most midline ventral skull base tumors. Pituitary adenomas and Rathke’s cleft cysts (RCCs) constitute the majority of lesions removed via this route; however, craniopharyngiomas, clival chordomas, midline meningiomas and other benign and malignant skull base tumors are now increasingly removed by this approach. Herein we describe the evolution of the endonasal endoscopic technique, its current use for sellar and midline skull base tumors and potential for future innovation.

Corresponding author: Daniel F. Kelly, MD, Brain Tumor Center and Pituitary Disorders Program, John Wayne Cancer Institute at Saint John’s Health Center, 2200 Santa Monica Blvd., Santa Monica, CA 90404, USA, Tel.: +1 310 582–7450, Fax: +1 310 582–7495

Received: 2012-10-23
Accepted: 2012-11-28
Published Online: 2013-01-14
Published in Print: 2013-02-01

©2013 by Walter de Gruyter Berlin Boston

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