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Licensed Unlicensed Requires Authentication Published by De Gruyter November 28, 2015

Intraventricular injectable tumor model for neuroendoscopic surgery: Laboratory Study

  • Anthony M.T. Chau , Filippo Gagliardi , Pietro Mortini , Samer K. Elbabaa and Cristian Gragnaniello EMAIL logo
From the journal Innovative Neurosurgery

Abstract

Intraventricular tumors present difficult challenges to the neurosurgeon. Neurosurgeons have begun to explore the possibilities of the endoscope in the complete resection of solid intraventricular tumors. The learning curve is considered steep when dealing with such lesions endoscopically. The aim of this study was to develop a laboratory training model for pathological intraventricular neuroendoscopic surgery. Thirty formalin-fixated, latex-injected cadaveric heads were used. The contrast-enhancing tumor polymer, Stratathane resin ST-504 derived polymer (SRSDP), was injected into the lateral ventricle via Frazer’s point under direct endoscopic visualization and real-time fluoroscopic guidance. Neurosurgeon participants at a ventricular endoscopic course then performed an endoscopic approach to the intraventricular tumor model lesion via an ipsilateral frontal burr hole. The properties of the SRSDP mixture could be manipulated through varying concentrations of source materials in order to achieve a desired consistency and allow for piecemeal resection. Tumor could be injected into the lateral and third ventricles. The tumor model allowed participants to compare both normal and pathological endoscopic anatomy in the one specimen. Our novel injectable tumor model can assist neurosurgeons preparing themselves for the challenges associated with a piecemeal resection of a solid lesion in the lateral or third ventricle.


Corresponding author: Dr. Cristian Gragnaniello, MD, PhD, MSurg, MAdSurg, Suite 201, 2 Technology Place, Macquarie University NSW 2109, Sydney, NSW, Australia, Tel.: +61 2 9812 3900, Fax: +61 2 9812 3898, E-mail: ; and Department of Neurosurgery, Macquarie University Hospital, Sydney, NSW, Australia

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The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2015-4-8
Accepted: 2015-11-12
Published Online: 2015-11-28
Published in Print: 2015-12-1

©2015 by De Gruyter

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