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Licensed Unlicensed Requires Authentication Published online by De Gruyter January 7, 2022

Diabetic wound healing approaches: an update

Raghuvir Keni, Farmiza Begum, Karthik Gourishetti, Gollapalle Lakshminarayanashastry Viswanatha, Pawan Ganesh Nayak, Krishnadas Nandakumar and Rekha R Shenoy


Diabetic wounds are of profound clinical importance. Despite immense efforts directed towards its management, it results in the development of amputations, following a diagnosis of diabetic foot. With a better understanding of the complexities of the microbalance involved in the healing process, researchers have developed advanced methods for the management of wounds as well as diagnostic tools (especially, for wound infections) to be delivered to clinics sooner. In this review, we address the newer developments that hope to drive the transition from bench to bedside in the coming decade.

Corresponding author: Rekha R Shenoy, Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India, E-mail:
Raghuvir Keni and Farmiza Begum contributed equally to this work.

  1. Research funding: None declared.

  2. Author Contribution: Conceptualization R.K.; Investigation R.K., K.G.; Original draft preparation R.K, F.B., K.G.; Review, and Editing G.L.V., K.G., P.N., R.R.S.; Image designing R.K.; Supervision K.N., R.R.S.

  3. Conflict of Interest: Authors declare no conflict of interest.


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Received: 2021-11-09
Accepted: 2021-12-19
Published Online: 2022-01-07

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