# Abstract

There are two general views in causal analysis of experimental data: the super population view that the units are an independent sample from some hypothetical infinite population, and the finite population view that the potential outcomes of the experimental units are fixed and the randomness comes solely from the treatment assignment. These two views differs conceptually and mathematically, resulting in different sampling variances of the usual difference-in-means estimator of the average causal effect. Practically, however, these two views result in identical variance estimators. By recalling a variance decomposition and exploiting a completeness-type argument, we establish a connection between these two views in completely randomized experiments. This alternative formulation could serve as a template for bridging finite and super population causal inference in other scenarios.

## 1 Introduction

Neyman [1, 2] defined causal effects in terms of potential outcomes, and proposed an inferential framework viewing all potential outcomes of a finite population as fixed and the treatment assignment as the only source of randomness. This finite population view allows for easy interpretation free of any hypothetical data generating process of the outcomes, and is used in a variety of contexts e.g., [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]. This approach is considered desirable because, in particular, it does not assume the data are somehow a representative sample of some larger (usually infinite) population.

Alternative approaches, also using the potential outcomes framework, assume that the potential outcomes are independent and identical draws from a hypothetical infinite population. Mathematical derivations under this approach are generally simpler, but the approach itself can be criticized because of this typically untenable sampling assumption. Furthermore, this approach appears to ignore the treatment assignment mechanism.

That being said, it is well known that the final variance formulae from either approach tend to be quite similar. For example, while the variance of the difference-in-means estimator for a treatment-control experiment under an infinite population model is different from the one under Neyman’s [1] finite population formulation, this difference is easily represented as a function of the variance of the individual causal effects. Furthermore, this difference term is unidentifiable and is often assumed away under a constant causal effect model ([1, 2, 23, 24, 25, 26]), or by appeals to the final estimators being “conservative.”

For the difference in means, the infinite population variance estimate gives a conservative (overly large) estimate of the finite population variance. As deriving infinite population variance expressions, relative to finite population variance expressions, tends to be more mathematically straightforward, we might naturally wonder if we could use infinite population expressions as conservative forms of finite population expressions more generally. In this work we show that in fact we can assume an infinite population model as an assumption of convenience, and derive formula from this perspective. This shows that we can thus consider the resulting formula as focused on the treatment assignment mechanism and not on a hypothetical sampling mechanism, i.e., we show variance derivations under the infinite population framework can be used as conservative estimators in a finite context.

Mathematically, this result comes from a variance decomposition and a completeness-style argument characterizing the connection and the difference between these two views. The variance decomposition we use has previously appeared in Imai [7], Imbens and Rubin [18], and Balzer et al. [27]. The completeness-style argument, which we believe is novel in this domain, then sharpens the variance decomposition by moving from an expression on an overall average relationship to one that holds for any specific sample.

Our overall goal is simple: we wish to demonstrate that if one uses variance formula derived from assuming an infinite population sampling model, then the resulting inference one obtains will be correct with regards to the analogous sample-specific treatment effects (although it could be potentially conservative in that the standard errors may be overly large) regardless of the existence of any sampling mechanism.

## 2 Super population, finite population, and samples

Assume that random variables

The individual causal effect for unit

At the super population level, the average potential outcomes are

The population variances of the potential outcomes and individual causal effect are

At the finite population level, i.e., for a fixed sample

The corresponding finite population variances of the potential outcomes and individual causal effects are

where, following the tradition of survey sampling [28], we use the divisor

Regardless, we have two parameters – the population average treatment effect

Our primary statistics are the averages of the observed outcomes and the difference-in-means estimator:

We also observe the sample variances of the outcomes under treatment and control using

We do not have the sample analogue of

We summarize the infinite population, finite population and sample quantities in Table 1.

### Table 1

Means | Variances | |||||
---|---|---|---|---|---|---|

Treatment | Control | Effect | Treatment | Control | Effect | |

Super population | ||||||

Finite population | ||||||

Sample |

## 3 Deriving complete randomization results with an independent sampling model

The three levels of quantities in Table 1 are connected via independent sampling and complete randomization. Neyman [1], without reference to any infinite population and by using the assignment mechanism as the only source of randomness, represented the assignment mechanism via an urn model, and found

He then observed that the final term was unidentifiable but nonnegative, and thus if we dropped it we would obtain an upper bound of the estimator’s uncertainty.

We next derive this result by assuming a hypothetical sampling mechanism from some assumed infinite super-population model of convenience. This alternative derivation of the above result, which can be extended to other assignment mechanisms, shows how we can interpret formulae based on super-population derivations as conservative formulae for finite-sample inference.

### 3.1 Sampling and randomization

To begin, note that IID sampling of

and third, the sample variances are unbiased estimates of the true variances:

Conditional on

We do not use the notation

If we do *not* condition on

This is the classic infinite population variance formula for the two sample difference-in-means statistic. We could use it to obtain standard errors by plugging in

### 3.2 Connecting the finite and infinite population inference with a variance decomposition

We will now extend the above to indirectly derive the result on the variance of

which further implies that the finite population variance of

Compare to the classic variance expression (1), which is this without the expectation. Here we have that *on average* our classic variance expression holds. Now, because this is true for any infinite population, as it is purely a consequence of the IID sampling mechanism and complete randomization, we can close the gap between eqs (1) and (8). Informally speaking, because eq. (8) holds as an average over many hypothetical super populations, it should also hold for any finite population at hand, and indeed it does, as we next show using a “completeness” concept from statistics [29].

### 3.3 A “Completeness” argument

First, define

a function of a fixed finite sample

For any given sample

According to eq. (10), the finite population variance

for some

Because

Similarly, because

Use the above to replace our cross terms of

where

Thus,

Because eq. (11) holds for any populations regardless of its values of

## 4 Discussion

Equation (8) relies on the assumption that the hypothetical infinite population exists, but eq. (1) does not. However, the completeness-style argument allowed us to make our sampling assumption only for convenience in order to prove eq. (1) by, in effect, dropping the expectation on both sides of eq. (8). Similar argument exists in the classical statistics literature; see Efron and Morris [30] for the empirical Bayes view of Stein’s estimator. While the final result is, of course, not new, we offer it as it gives an alternative derivation that does not rely on asymptotics such as a growing super population or a focus on the properties of the treatment assignment mechanism.

Using Freedman’s [8] results, Aronow et al. [12] considered a super population with

This decomposition approach also holds for other types of experiments. First, for a stratified experiment, each stratum is essentially a completely randomized experiment. Apply the result to each stratum, and then average over all strata to obtain results for a stratified experiment. Second, because a matched-pair experiment is a special case of a stratified experiment with two units within each stratum, we can derive the Neyman-type variance cf. ([7, 18]) directly from that of a stratified experiment. Third, a cluster-randomized experiment is a completely randomized experiment on the clusters. If the causal parameters can be expressed as cluster-level outcomes, then the result can be straightforwardly applied cf.([11, 17]). Fourth, for general experimental designs, the variance decomposition in eq. (6) still holds, and therefore we can modify the derivation of the finite population variance according to different forms of eqs (4) and (5).

In a completely randomized experiment, the finite population sampling variance of

Our discussion is based on the frequentists’ repeated sampling evaluations of the difference-in-means estimator for the average causal effect. In contrast, Fisher [34] proposed the randomization test against the sharp null hypothesis that

# Acknowledgements

We thank Dr. Peter Aronow (the Associate Editor) and three anonymous reviewers for helpful comments.

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**Published Online:**2017-4-27

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