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Licensed Unlicensed Requires Authentication Published by De Gruyter July 5, 2016

A potential case of remission of Parkinson’s disease

Karishma Smart EMAIL logo , Raymon Durso , Jonathan Morgan and Patrick McNamara

Abstract

We present the case of a 78-year-old male who, 16 years ago, was diagnosed with Parkinson’s disease (PD) by a neurologist. He initially presented with left-hand tremor, stooped posture, shuffling gait, and frequent falls, which eventually progressed to bilateral motor symptoms after 3 years. Since 2012, his symptoms and signs have almost completely remitted, and he has been off all pharmacotherapy for that time. The accuracy of the initial PD diagnosis is supported by an appropriate clinical presentation, history of positive response to Sinemet, and an abnormal SPECT DaT scan; thus this case suggests the possibility of remission of symptoms in some patients. We propose that the patient’s long history of meditation practice may have been one contributing factor of this improvement as meditation has been shown to release dopamine in the striatum.

Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission. This work was conducted at Boston VA Healthcare System, Jamaica Plain Campus at 150 S. Huntington Ave., Jamaica Plain, MA, 10461.

Research funding: This work was supported by The John Templeton Foundation under Grant #7733510.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

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Received: 2016-3-14
Accepted: 2016-5-24
Published Online: 2016-7-5
Published in Print: 2016-9-1

©2016 by De Gruyter

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