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Licensed Unlicensed Requires Authentication Published by De Gruyter May 21, 2019

Phytochemistry and neuroprotective effects of Eclipta alba (L.) Hassk

  • Samson Guenné , Nabèrè Ouattara , Noufou Ouédraogo , Alin Ciobica EMAIL logo , Adama Hilou and Martin Kiendrebéogo


Eclipta alba (L.) Hassk. or Eclipta prostrata (Linn.) or Eclipta erecta (Linn.) is an herbaceous plant well known in Asian as African traditional medicines. These extracts are used in traditional medicine for treatment of microbial diseases and certain metabolic disorders. This review aimed to investigate phytochemical profile and neuroprotective effects of E. alba (L.) Hassk. Several compounds belonging to the families of phenolics, alkaloids, terpenoids and polysaccharides have been isolated, identified or characterized from E. alba extracts. This plant has a diverse neuropharmacological profile. Thus, its extract improves cognitive deficits and also attenuated epileptic seizures. Phytomolecules implicated in these potentials are Eclalbasaponin II and luteolin, respectively. This document updates isolated and identified organic compounds from the extracts of E. alba and reviews their neuropharmacological activities.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis and interpretation of data; in the writing of the report or in the decision to submit the report for publication.


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Received: 2019-01-29
Accepted: 2019-03-06
Published Online: 2019-05-21

© 2019 Walter de Gruyter GmbH, Berlin/Boston

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