Skip to content
Licensed Unlicensed Requires Authentication Published by De Gruyter December 23, 2020

Yellow phosphorous ingestion cause liver dysfunction and internal bleeding: a case study

  • Lalramengmawii Mawii , Norah H. Vanlalhriatmawii and Khayati Moudgil EMAIL logo

Abstract

Objective

The purpose of this case report was to create awareness among scientific fraternity and those who are in the regular usage of the yellow phosphorous compound. Yellow phosphorus is an inorganic element that is poisonous to humans (yellowish, waxy, crystal-clear solid with a pungent odor).

Case presentation

The patient treatment chart was reviewed and the patient’s condition was evaluated daily. Consumption of toxic doses causes shock and cardiovascular failure within 2–3 h of ingestion, and peak levels are reached when distributed to all tissues after absorption. Here, we report a case of self-harm with the ingestion of rat killer paste, and the patient suffered internal bleeding and acute liver failure.

Conclusion

Rodenticides remain the primary cause of morbidity and mortality, internal bleeding is the major risks of rodenticide poisoning.


Corresponding author: Khayati Moudgil, B. Pharm, Pharm D(PB), Resident, Department of Pharmacy Practice, JSS Academy of Higher Education & Research, JSS College of Pharmacy, Ooty, 643001, Tamil Nadu, India, Mobile: +91 9489238815, E-mail:

  1. Research funding: None declared.

  2. Author contributions: The authors contributed equally.

  3. Conflict of interest: The authors declare none.

References

1. Mishra, AK, Devakiruba, NS, Jasmine, S, Sathyendra, S, Zachariah, A, Iyadurai, R. Clinical spectrum of yellow phosphorous poisoning in a tertiary care centre in South India: a case series. Trop Doct 2017;47:245–9. https://doi.org/10.1177/0049475516668986.Search in Google Scholar

2. Anupama, M, Kunal, M, Leena, N, Preeti, S. Acute hepatic failure due to yellow phosphorus ingestion. Indian J Pharmacol 2011;43:355–6.10.4103/0253-7613.81500Search in Google Scholar PubMed PubMed Central

3. Fernandez, OU, Canizares, LL. Acute hepatotoxicity from ingestion of yellow phosphorus containing fireworks. J Clin Gastroenterol 1995;21:139–42. https://doi.org/10.1097/00004836-199509000-00015.Search in Google Scholar

4. Smitha, B, Kumar, PK. N-acetyl cysteine in the management of Rodenticide Consumption - life saving?. J Clin Diagn Res 2015;9:OC10–13.Search in Google Scholar

5. Tenzin, T, Khayati, M. Psychosis and rodenticides: a case report. J Young Pharm 2018;10:374–6.10.5530/jyp.2018.10.83Search in Google Scholar

6. Pillay, VV. Modern medical toxicology, completely updated, revised and profusely illustrated, 4th ed. Hyderabad, India: Jaypee Brothers Medical Publishers; 2013:67–70 pp. Non-Metallic Chemical Poison.Search in Google Scholar

7. Kharkongor, MA, Mishra, AK, Ninan, KF, Iyadurai, R. Early use of intravenous N-acetylcysteine in treatment of acute yellow phosphorus poisoning. Curr Med Issues 2017;15:136–8. https://doi.org/10.4103/0973-4651.206530.Search in Google Scholar

8. Ravikanth, R, Sandeep, S, Philip, B. Acute yellow phosphorus poisoning causing fulminant hepatic failure with parenchymal hemorrhages and contained duodenal perforation. Indian J Crit Care Med 2017;21:238–42. https://doi.org/10.4103/ijccm.ijccm_410_16.Search in Google Scholar


Supplementary Material

The online version of this article offers supplementary material (https://doi.org/10.1515/jcim-2020-0140).


Received: 2020-06-14
Accepted: 2020-07-01
Published Online: 2020-12-23

© 2020 Walter de Gruyter GmbH, Berlin/Boston

Downloaded on 30.3.2023 from https://www.degruyter.com/document/doi/10.1515/jcim-2020-0140/html
Scroll Up Arrow