Abstract
Objective
To explore repurposing known natural products for managing patients with mild to moderate symptoms of COVID-19.
Case presentation
We present a case report of a middle aged woman, who was positive to COVID 19, with mild to moderate symptoms; who self –managed at home using well formulated herbal supplement (Combi-5) taken along with vitamin C and Zinc supplements. She recovered within a short time.
Conclusions
While we may not conclude from this report that Combi-5 was solely responsible for the recovery of the patient, we strongly believe that it played significant role through different mechanisms in facilitating early recovery from the infection. Further studies are needed to evaluate the phytochemical and pharmacological constituents of the supplement; investigate its direct effect(s) on SARS CoV-2 and conduct randomized controlled trial to elucidate its clinical benefits.
Acknowledgement
We thank the patient who volunteered to take the herbal supplement and for giving her consent to document this report.
-
Research funding: Nil.
-
Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
-
Competing interests: Nil.
References
1. Corona virus disease global update. Available from: https://www.worldometers.info/coronavirus/?utm_campaign=homeAdvegas1? [Accessed 12 Oct 2020].Search in Google Scholar
2. Orhan, IE, Deniz, FSS. Natural products as potential leads against coronaviruses: could they be encouraging structural models against SARS-CoV-2? Nat Prod Bioprospecting 2020;10:171–86. https://doi.org/10.1007/s13659-020-00250-4.Search in Google Scholar PubMed PubMed Central
3. Parmer, V. Herbal medicine: its toxic effect and drug interactions. The Indian Anaesthetics’ Forum; 2005:1–9 pp.Search in Google Scholar
4. WHO supports scientifically-proven traditional medicine. Available from: https://www.afro.who.int/news/who-supports-scientifically-proven-traditional-medicine [Accessed 8 Oct 2020].Search in Google Scholar
5. Africa Centers for Disease Control and Prevention. Statement on herbal remedies and mediciness for prevention and treatment of COVID-19. Available from: https://africacdc.org/download/statement-on-herbal-remedies-and-medicines-for-prevention-and-treatment-of-covid-19/ [Accessed 10 Oct 2020].Search in Google Scholar
6. Meghwal1, M, Goswami, TK. Chemical composition, nutritional, medicinal and functional properties of black pepper: a review. Open Access Sci Rep 2012;1:1–5.10.4172/scientificreports.172Search in Google Scholar
7. Yang, Y, Islam, MS, Wang, J, Li, Y, Chen, X. Traditional Chinese medicine in the treatment of patients infected with 2019-new coronavirus (sars-cov-2): a review and perspective. Int J Biol Sci 2020;16:1708–17. https://doi.org/10.7150/ijbs.45538.Search in Google Scholar PubMed PubMed Central
8. Akindele, AJ, Agunbiade, FO, Sofidiya, MO, Awodele, O, Sowemimo, A, Ade-Ademilua, O, et al.. COVID-19 pandemic: a case for phytomedicines. Nat Prod Commun 2020;15:1–9.10.1177/1934578X20945086Search in Google Scholar
9. Liu, X, Zhang, M, He, L, Li, YP, Kang, YK. Chinese herbs combined with western medicine for severe acute respiratory syndrome (SARS). Cochrane Database Syst Rev 2012;10. https://doi.org/10.1002/14651858.CD004882.pub3.Search in Google Scholar PubMed PubMed Central
© 2021 Walter de Gruyter GmbH, Berlin/Boston
