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BY-NC-ND 4.0 license Open Access Published by De Gruyter October 18, 2016

Inter-STOP symbol distances for the identification of coding regions

Carlos A. C. Bastos EMAIL logo , Vera Afreixo , Sara P. Garcia and Armando J. Pinho


In this study we explore the potential of inter-STOP symbol distances for finding coding regions in DNA sequences. We use the distance between STOP symbols in the DNA sequence and a chi-square statistic to evaluate the nonhomogeneity of the three possible reading frames and the occurrence of one long distance in one of the frames. The results of this exploratory study suggest that inter-STOP symbol distances have strong ability to discriminate coding regions in prokaryotes and simple eukaryotes.

Published Online: 2016-10-18
Published in Print: 2013-12-1

© 2013 The Author(s). Published by Journal of Integrative Bioinformatics.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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