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Licensed Unlicensed Requires Authentication Published by De Gruyter May 29, 2015

Tamoxifen-associated hirsutism: an unusual side effect in a 5-year-old girl with McCune-Albright syndrome

  • Heves Kırmızıbekmez EMAIL logo , Rahime Gül Yesiltepe Mutlu , Fatma Dursun and Şükriye Pınar İşgüven


Tamoxifen, a selective estrogen receptor modulator, has been used in the treatment of peripheral precoccious puberty. A 5-year and 3-month-old girl, diagnosed with McCune-Albright syndrome, came in with abnormal hair growth approximately 2 months after the initiation of tamoxifen. The pattern of terminal hair on the skin following the administration of the drug and the exclusion of other causes suggested tamoxifen-induced hirsutism.

Corresponding author: Heves Kırmızıbekmez, Zeynep Kamil Obstetrics and Children Education and Research Hospital, Pediatric, Endocrinology, Barbaros mah. Sedef sok. No:3-E D:15, Üsküdar İstanbul, Turkey, Phone: +216 3910680, Mobile: +505 8148802, E-mail:


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Received: 2014-10-18
Accepted: 2015-4-9
Published Online: 2015-5-29
Published in Print: 2015-9-1

©2015 by De Gruyter

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