Skip to content
Licensed Unlicensed Requires Authentication Published by De Gruyter April 7, 2016

Childhood parathyroid adenoma: a rare but important cause of nephrolithiasis

Prema Menon, Devi Dayal, Suhitha G. Rao, Anish Bhattacharya and Katragadda Lakshmi Narasimha Rao


Primary hyperparathyroidism is very rare in children and adolescents. The management of a 12-year-old boy with renal calculi due to parathyroid adenoma is discussed. The single tumor after localization with sestamibi scintigraphy and SPECT-CT scan was excised with amelioration of symptoms. The case is reported due to the rarity of the disease and successful unilateral exploration. The association with hypopigmented areas of skin has also not been previously reported in literature.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


1. Durkin ET, Nichol PF, Lund DP, Chen H, Sippel RS. What is the optimal treatment for children with primary hyperparathyroidism? J Ped Surg 2010;45:1142–6.Search in Google Scholar

2. Kollars J, Zarroug AE, van Heerden J, Lteif A, Stavlo P, et al. Primary hyperparathyroidism in pediatric patients. Pediatrics 2005;115:974–80.Search in Google Scholar

3. Harman CR, van Heerden JA, Farley DR, Grant CS, Thompson GB, et al. Sporadic primary hyperparathyroidism in young patients: a separate entity? Arch Surg 1999;134:651–5.Search in Google Scholar

4. Eklioglu BS, Atabek ME, Akyurek N. Parathyroid adenoma presented with multiple brown tumors and nephrocalcinosis. J Pediatr Endocrinol Metab 2013;26:213–4.Search in Google Scholar

5. Libansky P, Astl J, Adamek S, Nanka O, Pafko P, et al. Surgical treatment of primary hyperparathyroidism in children: report of 10 cases. Int J Pediatr Otorhinolaryngol 2008;72:1177–82.Search in Google Scholar

6. Sneider MS, Solorzano CC, Montano RE, Anello C, Irvin GL, et al. Sporadic primary hyperparathyroidism in young individuals different disease and treatment? J Surg Research 2009;155:100–3.Search in Google Scholar

7. Shah VN, Bhadada SK, Bhansali A, Behera A, Mittal BR, et al. Influence of age and gender on presentation of symptomatic primary hyperparathyroidism. J Postgrad Med 2012;58:107–11.Search in Google Scholar

8. Fuleihan GE, Rubeiz N. Dermatological manifestations of parathyroid-related disorders. Clin Dermatol 2006;24:281–8.Search in Google Scholar

9. Simsek E, Arikan Y, Dallar Y, Akkus MA. Prolonged hungry bone syndrome in a 10-year-old child with parathyroid adenoma. Indian Pediatr 2009;46:178–80.Search in Google Scholar

10. Profanter C, Wetscher GJ, Gabriel M, Sauper T, Rieger M, et al. CT-MIBI image fusion: a new preoperative localization technique for primary, recurrent, and persistent hyperparathyroidism. Surgery 2004;135:157–62.Search in Google Scholar

11. Mollerup CL, Lindewals H. Renal stones and primary hyperparathyroidism: natural history of renal stone disease after successful parathyroidectomy. World J Surg 1999;23:173–5.Search in Google Scholar

Received: 2015-9-13
Accepted: 2016-2-9
Published Online: 2016-4-7
Published in Print: 2016-7-1

©2016 by De Gruyter