Pros of priming in the diagnosis of growth hormone deficiency:

E. Nazli Gonc; Alev Ozon; Ayfer Alikasifoglu; Nurgun Kandemir

doi:10.1515/jpem.2011.076

Published by De Gruyter March 16, 2011

Pros of priming in the diagnosis of growth hormone deficiency

E. Nazli Gonc , Alev Ozon , Ayfer Alikasifoglu and Nurgun Kandemir

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https://doi.org/10.1515/jpem.2011.076

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Abstract

Priming with sex steroids in stimulation tests for the diagnosis of GHD is still under debate. Most of the data on utility of priming during GH stimulation so far seem to support its use in the diagnosis of GHD in childhood. There is a propensity to treat growth retarded children who test subnormally to stimulation tests with GH. However, some studies analyzing the final height or height gain during GH treatment in such children failed to show any improvement in height. This paper summarizes previous studies on priming to analyze the utility of priming as a valid method to better the diagnostic capacity of the test.

Keywords: final height; growth hormone; growth hormone deficiency; growth hormone stimulation tests; priming; sex steroids

Corresponding author: E. Nazli Gonc, Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey Phone: +903123051124, Fax: +903123121809

Published Online: 2011-03-16

Published in Print: 2011-03-01

Pros of priming in the diagnosis of growth hormone deficiency

Abstract

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