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Licensed Unlicensed Requires Authentication Published by De Gruyter March 16, 2011

Benign transient hyperphosphatasemia in infants and children: a prospective cohort

  • Jonathan E. Teitelbaum EMAIL logo , Alexandra Laskowski and Frank P. Barrows
From the journal


A total of 20 children with benign transient hyperphosphatasemia were prospectively evaluated with no additional investigations recommended except repeat serologic evaluation in 2–3 months. The average age of our patients was 2.5 years (range: 1 year 2 months–5 years 10 months). The serum levels of alkaline phosphatase averaged 2383 IU/L (range: 1013–5700 IU/L). Levels returned to normal within several months. This condition should be recognized by the clinician in order not to put patients through lengthy, expensive and unnecessary investigations.

Corresponding author: Jonathan E. Teitelbaum, MD, Department of Pediatrics, The Children’s Hospital at Monmouth Medical Center, 300 Second Ave, Long Branch, NJ 07750, USA Phone: +1-732-923-6080, Fax: +1-732-923-6083

Published Online: 2011-03-16
Published in Print: 2011-03-01

©2011 by Walter de Gruyter Berlin New York

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