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Licensed Unlicensed Requires Authentication Published by De Gruyter March 16, 2011

Abdominal obesity is associated with cardiovascular risk in Japanese children and adolescents

  • Satoru Iwashima EMAIL logo , Yuichi Nakagawa , Takamichi Ishikawa , Shinichirou Sano Eiichiro Satake , Eiko Nagata and Takehiko Ohzeki
From the journal


Background: Metabolic syndrome is listed as a risk for atherosclerosis. However, changes in that risk during childhood and adolescence have not been well-documented. It is also unclear whether individuals with abdominal obesity, but with as yet undiagnosed metabolic syndrome, have cardiovascular risks.

Methods and results: Ninety-two patients were studied at the Hamamatsu University School of Medicine Department of Pediatrics. Physical measurements including abdominal circumference (AC), body mass index (BMI), body fat (BF), intima media thickness (IMT), arterial elasticity: beta index (Beta), carotid artery compliance (CAC), and Young’s elastic modulus (YEM) using ultrasonography were taken. A positive correlation between systolic blood pressure, AC, BMI, and BF was observed (AC, r=0.717, p<0.001; BMI, r=0.672, p<0.001; BF, r=0.518, p<0.001). IMT showed a weak positive correlation with AC, BMI and BF (AC, r=0.211, p=0.044; BMI, r=0.233, p=0.025; BF, r=0.232, p=0.026). The relationship between AC, BMI, BF and arterial elasticity, especially in AC, positively correlated with beta index and YEM but negatively correlated with CAC.

Conclusion: We suggest that AC is the most sensitive marker in the detection of arterial elasticity, even in school age children. Earlier pre-diagnostic intervention, especially in the prevention of abdominal obesity, may reduce the incidence of metabolic syndrome in children and adolescents.

Corresponding author: Satoru Iwashima, Department of Pediatrics, Hamamatsu University, School of Medicine, Handayama 1-20-1, Hamamatsu City 431-3192, Japan Phone: +81-53-435-2312, Fax: +81-53-435-2111

Published Online: 2011-03-16
Published in Print: 2011-03-01

©2011 by Walter de Gruyter Berlin New York

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